Non-steroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy

Siviter, Gretchen; Cardwell, Mary; Smith, Austin

doi:10.1002/14651858.cd003591

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2015

2024

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Cited by 2 publications

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“…Non-steroidal anti-inflammatory drugs might be an option but concern has been expressed about the risk of increased bleeding with these drugs. One review of 15 randomised studies and 1100 children by Lewis 2013 showed that there was a non-significant increase in bleeding.…”

Section: Discussionmentioning

confidence: 99%

As required versus fixed schedule analgesic administration for postoperative pain in children

Hobson

Wiffen

Conlon

2015

Cochrane Database of Systematic Reviews

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Section: Discussionmentioning

confidence: 99%

As required versus fixed schedule analgesic administration for postoperative pain in children

Hobson

Wiffen

Conlon

2015

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

show abstract

Incidence of Surgically Managed Post-Tonsillectomy Hemorrhage Associated With NSAID Prescribing for Postoperative Pain Management

Jacobson,

Mack,

Herrera

et al. 2024

Military Medicine

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Introduction Tonsillectomy ranks high among the most common pediatric surgical procedures in the United States. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), such as ibuprofen, are routinely prescribed to manage post-tonsillectomy pain, but may carry the risk of hemorrhage. Materials and Methods This retrospective, longitudinal, secondary-data analysis study compared the incidence of surgically managed post-tonsillectomy hemorrhage (sPTH) in pediatric patients prescribed ibuprofen at Brooke Army Medical Center (BAMC) after tonsillectomy compared to a similar cohort of pediatric patients at the Children’s Hospital of Philadelphia (CHOP) not prescribed ibuprofen. Additional regression analysis examined predictors of sPTH at BAMC. Results The odds of sPTH was lower in patients who were prescribed ibuprofen at BAMC, relative to patients who were not at CHOP (OR 0.57, 95% CI, 0.37, 0.87; P < 0.01). In a generalized linear model evaluating BAMC patient data, there was a lack of a relationship between reason for tonsillectomy (tonsillitis versus tonsillar obstruction), primary procedure (tonsillectomy-only versus tonsillectomy with adenoidectomy), and presence of a co-occurring procedure. Conclusions Post-tonsillectomy ibuprofen prescribing practices were not associated with an elevated risk of sPTH, relative to patients at CHOP not exposed to ibuprofen.

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Non-steroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy

Cited by 2 publications

References 6 publications

As required versus fixed schedule analgesic administration for postoperative pain in children

As required versus fixed schedule analgesic administration for postoperative pain in children

Incidence of Surgically Managed Post-Tonsillectomy Hemorrhage Associated With NSAID Prescribing for Postoperative Pain Management

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