“…The order of magnitude of ℓ is assumed to be 200 μm, i.e., the diameter of trabeculae that are the elements of which the microstructure is made of (see, for more details on lattice structures similar to the trabecular bone, [ 10 ]). The second gradient continuum model may be deduced using an homogenization technique that through a micro-macro identification permit to obtain an equivalent model that predicts at the macro scale the response of the material due to the microstructure existing at micro-scale (see e.g., [ 26 , 52 , 53 , 54 , 55 , 56 , 57 ]). In this context, some critical issues related to the rise of damage in the system constituted by bone tissue and bio-material can be taken into account (see e.g., [ 58 , 59 , 60 , 61 , 62 , 63 , 64 ]).…”