Non‐specific senile dementia mimicking Huntington's disease in two siblings

Postmortem examination of an elderly male with cortical blindness and features of both cortical and subcortical dementia revealed extensive neuronal dropout most marked in the occipital cortex, moderate gliosis, rare neuritic plaques, no neurofibrillary tangles, and extensive Congophilic angiopathy. The unprecedented association of Congophilic angiopathy with nonspecific dementia provides further support for the concept that Congophilic angiopathy is usually a nonspecific manifestation of neuronal degeneration and of little clinical significance except when it results in intracerebral hemorrhage.

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Nonspecific dementia, cortical blindness, and Congophilic angiopathy

Nadeau

Bebin

Smith

1987

J Neurol

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Causes of organic dementia: a necropsy survey of 60 cases

Ojeda

Mastaglia

Kakulas

1986

Medical Journal of Australia

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Non‐specific senile dementia mimicking Huntington's disease in two siblings

Cited by 2 publications

References 5 publications

Nonspecific dementia, cortical blindness, and Congophilic angiopathy

Nonspecific dementia, cortical blindness, and Congophilic angiopathy

Causes of organic dementia: a necropsy survey of 60 cases

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