Non-small-cell lung cancer with multiple paraneoplastic syndromes

Monsieur, I; Meysman, Marc; Noppen, Marc; Grève, Jacques De; Delhove, O; Velckeniers, B; Jacobvitz, D; Vincken, Walter

doi:10.1183/09031936.95.08071231

Cited by 25 publications

(13 citation statements)

References 6 publications

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“…Although paraneoplastic disorders can involve any organic system of the human body, the involvement of the neurological system is extremely rare [3, 6, 7]. …”

Section: Discussionmentioning

confidence: 99%

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A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss

Argyriou

Peters

Ishtiaq

et al. 2012

Case Reports in Medicine

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Paraneoplastic syndromes are rare initial manifestations of a neoplastic disorder that may precede the actual detection of an overt cancer. These syndromes can generally involve any organic system of the human body with gastroparesis being the commonest manifestation of the paraneoplastic involvement of the neuronal bodies of the gastrointestinal tract in cancer patients. Gastroparesis is the result of an autoimmune destruction of the nerve plexus of the stomach that causes nonspecific gastrointestinal symptoms such as intractable vomiting and abdominal discomfort that interfere with patients' quality of life and are often ascribed to psychological factors. Thus, if not suspected, it easily evades the diagnostic thought especially in those cases where the diagnostic work up has not detected any apparent cause. Consequently, it should always be considered in patients with diagnosed or suspected cancer who complain of unexplained gastrointestinal symptoms. In our report, so as to increase the clinical awareness of this rare clinical entity, we present the case of a 70-year-old Caucasian female who presented in our hospital with severe gastroparesis that was later proven to be associated with an overt small cell lung cancer (SCLC) and we discuss the existing knowledge of the pathophysiology, diagnosis, and management of this disorder.

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“…Although paraneoplastic disorders can involve any organic system of the human body, the involvement of the neurological system is extremely rare [3, 6, 7]. …”

Section: Discussionmentioning

confidence: 99%

“…Among different types of malignancy, lung cancer, SCLC in particular, is the type which is more often associated with the development of a paraneoplastic disorder of the nervous system [3, 6, 7]. …”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss

Argyriou

Peters

Ishtiaq

et al. 2012

Case Reports in Medicine

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“…We report a 37-year-old patient with long-term nicotine abusus, who attracted attention by symptoms of a Der interessante Fall "007", 11.3.02/dk Köthen GmbH rinii-Infektion ist das Syndrom beschrieben. Hauptsächlich wird es aber als paraneoplastisches Syndrom [9,10] bei Tumorerkrankungen der Lunge, der Pleura und des Mediastinums gefunden, besonders beim Bronchialkarzinom [1,4,5,6,7,11,13]. Auch beim Lungensarkom [7], bei Lungenmetastasen [3] nach diversen epithelialen und mesenchymalen Malignomen, bei Thymuskarzinomen [7], bei M. Hodgkin, bei Mammakarzinom und Larynxkarzinom [2], bei Bronchuskarzinoid, bei benignem und malignem solitären fibrösen Pleuratumor oder bei Ösophaguskarzinomen [7] und Endocarditis Osler wurde das Syndrom beschrieben.…”

Section: Discussionunclassified

Pierre-Marie-Bamberger Syndrom - Ein paraneoplastisches Syndrom beim Bronchialkarzinom - Ein Fallbericht -

Düster

2002

Zentralbl Chir

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The Pierre-Marie-Bamberger syndrome is a rare paraneoplastic syndrome caused by bronchial carcinoma. Typical signs are symmetric periostoses on the diaphyses of the long tubular bones, clubbed fingers and toes with eye-glass shape of the nails, neuro-vegetative disturbances and dysproteinemia. We report a 37-year-old patient with long-term nicotine abusus, who attracted attention by symptoms of a Pierre-Marie-Bamberger syndrome. Further diagnostics revealed a tumor in the apex of the left lung. After lobectomy of the upper lobe of the left lung the symptoms are completly disappeared.

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“…Solid tümörler Ekinci ve ark. Paraneoplastik özellik gösteren reaktif dermatozlar ise akciğer kanseri (5 olgu), meme kanseri (2 olgu), gastrointestinal kanserler (3 olgu), prostat kanseri (2 olgu), peritoneal kanser (1 olgu), nazofarengeal kanser (1 olgu) ve karsinoid tümör (1 olgu) olarak belirtilmiştir 22,[33][34][35][36][37][38] . Bu 40 olgunun yaş ortalaması 55 olup %64'ü kadındır.…”

Section: Eritem Anüler Santrifüjunclassified

Paraneoplastik özellik gösteren reaktif dermatozlar

Ekinci¹,

Aslan²

2013

TURKDERM

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ÖzetReaktif dermatozlar infeksiyonlar, inflamatuar hastalıklar, ilaç kullanımı ve maligniteler başta olmak üzere birçok nedenle ortaya çıkabilirler. Böyle bir dermatozla karşılaşan hekimler dermatozu tedavi etmenin yanı sıra altta yatan nedeni araştırmaya da yönelirler. Bu derlemede, reaktif dermatozların paraneoplastik potansiyelleri değerlendirilerek tanı sonrası etyoloji, takip ve tedavide yapılması gerekenler irdelenmiştir. Sum maryReactive dermatoses may occur related to many underlying causes including infections, inflammatory diseases, medications and malignancies. In the management of these dermatoses the investigation of underlying cause is crucial besides the therapy of dermatosis. In this review, mainly the paraneoplastic potentials of reactive dermatoses have been evaluated and additionally the etiology, follow-up and treatment have been discussed. Recent literature about figurated erythemas (erythema annulare centrifugum, erythema gyratum repens, necrolytic migratory erythema), neutrophilic dermatoses (Sweet's syndrome, pyoderma gangrenosum, subcorneal pustular dermatosis) and erythema nodosum have been scrutinized. (Turkderm 2013; 47: Suppl 2: 69-77) Key Words: Paraneoplasia, reactive dermatoses, Sweet syndrome, erythema gyratum repens, necrolytic migratory erythema, erythema annulare centrifugum, subcorneal pustular dermatosis, erythema nodosum, pyoderma gangrenosum

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Non-small-cell lung cancer with multiple paraneoplastic syndromes

Abstract: N No on n--s sm ma al ll l--c ce el ll l l lu un ng g c ca an nc ce er r w wi it th h m mu ul lt ti ip pl le e p pa ar ra an ne eo op pl la as st ti ic c s sy yn nd dr ro om me es s

Cited by 25 publications

References 6 publications

A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss

A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss

Pierre-Marie-Bamberger Syndrom - Ein paraneoplastisches Syndrom beim Bronchialkarzinom - Ein Fallbericht -

Paraneoplastik özellik gösteren reaktif dermatozlar

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