Non-pharmacological strategies to alleviate dysgeusia in patients undergoing chemotherapy: A systematic review

Mazzoleni, Beatrice; Ferrari, Giulia; Savioni, Francesca; Gravante, Francesco; Lopane, Diego; Dacomi, Alessandra; Coldani, Chiara; Tomaiuolo, Giuseppina; Cattani, Daniela; Anastasi, Giuliano; Mancin, Stefano

doi:10.1016/j.ejon.2024.102569

Cited by 2 publications

(1 citation statement)

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“…Nutrition assumes a critical role before surgery, especially among patients who may have undergone neoadjuvant chemotherapy treatments. Such individuals often face nutritional challenges like appetite loss, nausea, vomiting, and alterations in taste perception [ 31 , 32 ], underscoring the importance of addressing nutritional needs as part of a comprehensive and targeted preoperative management. As elucidated by two studies, [ 33 , 34 ] oral supplements and immunonutrition emerge as promising treatments for mitigating postoperative complications and expediting recovery in RC patients.…”

Section: Discussionmentioning

confidence: 99%

Nutritional Prehabilitation in Patients Undergoing Cystectomy: A Systematic Review

Dal Bello,

Mancin,

Morales Palomares

et al. 2024

Nutrients

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Background/Aim: Nutrition is a key element of the prehabilitation process prior to surgery. The aim of this study was to identify the clinical pathways of nutritional prehabilitation before cystectomy. Methods: A systematic literature review was conducted in PubMed, the Cochrane Library, CINAHL, Scopus and the Web of Science databases. Quality and risk of bias assessment was conducted adhering to the JBI framework and evidence was evaluated according to the Oxford Centre for Evidence Based Medicine levels of evidence. Results: Out of 586 records identified, six studies were included. Among them, only two were randomized controlled trials. Immunonutrition has been shown to improve postoperative bowel function (3.12 vs. 3.74 days; RR 0.82; CI, 0.73–0.93; p = 0.0029) and decrease postoperative complications (−36.7%; p = 0.008) and readmission rates (−15.38%; p = 0.03). Furthermore, oral nutritional supplements combined with nutritional counseling demonstrated an accelerated recovery of bowel function (−1 day; p < 0.01), a reduction in the length of hospital stay (−1.75 days; p = 0.01), an improvement in handgrip strength (+6.8%, p < 0.001), an increase in bone mass (+0.3 kg, p = 0.04), and a better BMI value (+2.3%, p = 0.001). Conclusions: Nutritional prehabilitation demonstrates potential in enhancing postoperative outcomes following radical cystectomy. Oral supplements, immunonutrition, and counseling exhibit efficacy in improving postoperative results.

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