Non-odontogenic hard palate cysts with special reference to globulomaxillary cyst

Abstract

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Globulomaxillary cyst: does it still exist? A case report

“…the trapped epithelium because of the fusion of upper jaw bones and those of odontogenic origin which arise from tooth developing epithelium. The first category includes the globulomaxillary, nasopalatine, median palatal and nasolabial (naso alveolar) cysts and the second includes the dentigerous cysts, primordial cysts, odontogenic keratocysts and residual cysts 9 . Globulomaxillary cysts are fissural cysts of nonodontogenic origin which are located in the globular and maxillary process fusion area, with an etiopathogenesis similar to that of oral and facial clefts 1,4 .…”

“…Globulomaxillary cysts are fissural cysts of nonodontogenic origin which are located in the globular and maxillary process fusion area, with an etiopathogenesis similar to that of oral and facial clefts 1,4 . The most likely cause seems to be an epithelial entrapment between the nasal and maxillary process, as they are categorized as nonodontogenic cysts 9 . However, many kinds of tumors might develop in the globulomaxillary area, such as periodontal cysts, radicular cysts and keratocystic or adenomatoid odontogenic tumours 1 .…”

“…The mass in our case followed all the above-mentioned criteria, leading to a safe diagnosis. As no other nomenclature can describe such a lesion, we adopt the term "globulomaxillary cyst" in accordance with other similar studies 4,[8][9][10][11][12] . According to Huston et al in 2017, such a type of cyst presents specific features that cannot match to other potential diagnoses 8 .…”

“…Rarely, a globulomaxillary cyst might enter the nasal cavity [9][10]19 causing nasal obstruction, bleeding, inflammation and cosmetic deformity. Thus, the certain diagnosis and rapid treatment with excision of the cyst are essential 1,9 . The excision can be a simple procedure performed by sub-labial approach, which helps avoiding any cosmetic deformity.…”

“…Since then, several studies propose the elimination of the term as a self-sufficient entity 1,7 . Nevertheless, there are more than a few reports in the literature of true globulomaxillary cysts which cannot be ignored 2,[8][9][10][11][12] .…”