Non-neoplastic Lesions of the Uterine Corpus

Clement, Philip B.; Young, Robert H.

doi:10.1016/b978-1-4160-2972-4.50011-8

Cited by 1 publication

(2 citation statements)

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“…Pathologically, adenomyosis is characterized by the presence of endometrial glands within the myometrium and often accompanies a smooth muscle hyperplasia with a diffusely thickened, trabeculated myometrium. 1 , 21 Given the microscopic muscular changes in adenomyosis, one would expect changes, to some extent, in the layer of restricted water diffusion. Our observations revealed, however, that this layer was preserved in nearly half of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…It is characterized by the presence of ectopic endometrial glands and stroma below the endometrial-myometrial junction (EMJ). 1 , 2 Pathologically, endometrial glands and stroma are typically surrounded by hyperplastic myometrium. 1 Therefore, on T 2 -weighted (WI) images in magnetic resonance imaging (MRI), a diffuse or focal thickening of the junctional zone (JZ) with irregular margins can be observed, as well as a low-signal-intensity area in the inner myometrium.…”

Section: Introductionmentioning

confidence: 99%

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A Layer of Decreased Apparent Diffusion Coefficient at the Endometrial-Myometrial Junction in Uterine Adenomyosis

Kido

Fujimoto

Matsubara

et al. 2016

MRMS

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Objectives:To assess the detectability of a low-signal-intensity line within adenomyosis lesions adjacent to the endometrium on apparent diffusion coefficient (ADC) maps, and to establish correlations between these lesions and their possible causes, and more particularly the hormonal changes and magnetic resonance (MR) factors.Materials and methods:MR images were obtained from 110 patients with adenomyosis (age 30–57 y.o.) using 3.0 T or 1.5 T MR units. Recognition of the low-signal-intensity line on ADC map was scored using confidence level. The correlation between recognition of the line and the following factors were examined: magnetic field strength, age group, menstrual cycle phases, history of delivery, and hormonal treatments. Presence of the structure corresponding to the low-signal-intensity line on ADC map was evaluated pathologically in the cases that underwent surgery.Results:The low-signal-intensity line visible on ADC map was recognized in 55/110 patients. The visibility of the line was not significantly related to hormonal status, age, history of delivery, or magnetic resonance imaging (MRI) magnet strength. There were no corresponding pathological structures.Conclusion:One half of the adenomyosis patients showed discrepant appearances in T2-weighted (T2WI) vs. ADC map, but no significant relationship with hormonal changes was found in this study. This result may suggest that the low-signal-intensity line within the junctional zone may be related to a functional phenomenon.

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Section: Discussionmentioning

confidence: 99%