Non-Multidrug-Resistant, Methicillin-Resistant Staphylococcus aureus in a Neonatal Unit

García, Camila; Rosa, Juliana Fernandes; Cursino, Maria Aparecida; Lobo, R.; Mollaco, Carla H.; Gobara, S.; Malieno, Paula B.; Raymundo, Gabriela F.; Soares, Robson E.; Keil, Kleiste G.; Toma, Edi; Salomão, Matias Chiarastelli; Matté, Maria Helena; Krebs, Vera Lúcia Jornada; Gibelli, Maria Augusta Bento Cicaroni; Kondo, Marcel Yuzo; Zugaib, Marcelo; Costa, Sílvia Figueiredo; Levin, Anna S.

doi:10.1097/inf.0000000000000435

Cited by 8 publications

(16 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This rate is similar to what has been observed in other studies. 20 , 33 However, the prevalence of MRSA was 5.7%, which is higher than that has been observed in other studies. 13 , 33 , 34 The prevalence of S. aureus vaginal carriage in pregnant women was 7.3%, which was higher than that in an American study (2.3%, 10/432), 35 a Colombian study (5.0%, 5/100), 36 and a French study (5.9%, 67/1139).…”

Section: Discussioncontrasting

confidence: 60%

“… 20 , 33 However, the prevalence of MRSA was 5.7%, which is higher than that has been observed in other studies. 13 , 33 , 34 The prevalence of S. aureus vaginal carriage in pregnant women was 7.3%, which was higher than that in an American study (2.3%, 10/432), 35 a Colombian study (5.0%, 5/100), 36 and a French study (5.9%, 67/1139). 17 The prevalence of MRSA vaginal carriage in pregnant women was 1.7%, which is higher than that in two American studies ([0.2%, 1/432] 35 and [0.7%, 19/2702] 12 ), a Colombian study (1.0%, 1/100), 36 a Chinese study (0.5%, 15/2963), 9 and a Japanese study (0%, 0/4067).…”

Section: Discussioncontrasting

confidence: 60%

See 1 more Smart Citation

A prospective cohort study of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in neonates: the role of maternal carriage and phenotypic and molecular characteristics

Lin¹,

Wu²,

Yan³

et al. 2018

IDR

View full text Add to dashboard Cite

BackgroundStaphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), in mothers can cause serious outcomes in neonates. We aimed to elucidate the associations of S. aureus and MRSA carriage between mothers and neonates.MethodsA prospective cohort study was conducted between August and November 2015 in two hospitals in Shenzhen, China. Chinese pregnant women and their neonates who met the inclusion criteria were included in this study; samples and relevant information were collected. We assessed maternal–neonatal associations by using Poisson regression models.ResultsOverall, 1834 mothers and their neonates were included in this study. The prevalence of isolate carriage among the mothers was as follows: S. aureus (nasal, 25.8%; vaginal, 7.3%; and nasal and vaginal, 3.3%) and MRSA (nasal, 5.7%; vaginal, 1.7%; and nasal and vaginal, 0.5%). The incidences of S. aureus and MRSA carriage among neonates were 3.3% and 0.8%, respectively. Of the 21 maternal–neonatal pairs with S. aureus carriage, 14 were concordant pairs with the same phenotypic and molecular characteristics. After adjustment, the relative risks and 95% confidence intervals (CIs) between the S. aureus carriage of neonates and nasal S. aureus carriage, vaginal S. aureus carriage, and both nasal and vaginal S. aureus carriage of mothers were 2.8 (95% CI, 1.6–4.8), 7.1 (95% CI, 4.1–12.4), and 9.6 (95% CI, 4.2–22.4), respectively.ConclusionS. aureus carriage in mothers increases the risk for neonates.

show abstract

Section: Discussioncontrasting

confidence: 60%

Section: Discussioncontrasting

confidence: 60%

A prospective cohort study of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in neonates: the role of maternal carriage and phenotypic and molecular characteristics

Lin¹,

Wu²,

Yan³

et al. 2018

IDR

View full text Add to dashboard Cite

show abstract

“…In addition, the prevalence of MRSA infections and colonization among pregnant women have increased [ 8 , 9 , 10 ]. Similarly, the number of reports linking MRSA with outbreaks in newborn nurseries and neonatal intensive care units are also increasing [ 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Dominance of community-associated methicillin-resistant Staphylococcus aureus clones in a maternity hospital

Udo

Al‐Sweih

2017

PLoS ONE

View full text Add to dashboard Cite

BackgroundMethicillin- resistant Staphylococcus aureus (MRSA) is a major pathogen causing healthcare- and community- acquired infections. The purpose of this study was to characterize MRSA isolated at the Maternity Hospital between 2006 and 2011 for their genetic relatedness.Materials and methodsThe MRSA isolates were investigated using a combination of antibiogram, Staphylococcal chromosome cassette mec (SCCmec) and spa typing to determine their relatedness to MRSA isolated in other Kuwait hospitals. The isolates were also investigated for the carriage of genes for Pantone valentine Leukocidin (PVL).ResultsA total of 103 MRSA obtained from 64 neonates, 17 adult patients and 12 healthcare workers. The isolates were resistant to Kanamycin (46.6%), gentamicin (40.8%), trimethoprim (32%), ciprofloxacin (22.3%), fusidic acid (16.5%), tetracycline (19.4%), erythromycin (15.5%), clindamycin (15.5%), streptomycin (11.6%) high-level mupirocin (2.9%) and chloramphenicol (0.9%). Twenty (19.4%) of the isolates were multiresistant. Thirty-one (30.0%) isolates were positive for PVL. Molecular typing revealed the presence of 11 clonal complexes and 23 clones with ST5-V-t002, (N = 22), ST22-IV-t223 (N = 18), ST22-IV-t852 (N = 10), ST80-IV-t044 (N = 7), ST5-V-t688 (N = 5), ST772-V-t657 (N = 5) and ST239-III-t860 (N = 4) constituting 66.9% of the isolates. Other clones were isolated sporadically. The number of MRSA isolates increased from two in 2006 to 22 in 2011 with a peak of 43 in 2008.ConclusionThe study revealed a high prevalence of community-associated MRSA Maternity hospital. The MRSA population consisted of known strains, such as ST239-III-t680, ST22-IV-t223/t852 and ST80-IV-t044, that were reported previously in Kuwait and novel strains such as ST5-V-t002, and several sporadic strains obtained for the first time in the Maternity hospital. This study has provided an initial data which will serve as a platform for future comparative studies on the distribution of MRSA clones in the Maternity hospital in Kuwait.

show abstract

“…Mothers of preterm neonates often visit the neonatal intensive care unit (NICU) where their neonates are hospitalized (Gonya & Nelin, 2013). Persistent and predominant strains of staphylococci that cause LOS reside in the NICU on the surfaces of commonly touched areas (Achermann et al, 2015) and in the air (Botelho et al, 2012) and colonize the hands of healthcare workers (Garcia et al, 2014) and neonates (Soeorg et al, 2017). These bacterial sources may allow for transmission of nosocomial strains to the parents of hospitalized neonates, as has been reported for outbreaks of Staphylococcus aureus strains (Conceição et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates

et al. 2017

View full text Add to dashboard Cite

show abstract

Non-Multidrug-Resistant, Methicillin-Resistant Staphylococcus aureus in a Neonatal Unit

Cited by 8 publications

References 36 publications

A prospective cohort study of <em>Staphylococcus aureus </em>and methicillin-resistant <em>Staphylococcus aureus </em>carriage in neonates: the role of maternal carriage and phenotypic and molecular characteristics

A prospective cohort study of <em>Staphylococcus aureus </em>and methicillin-resistant <em>Staphylococcus aureus </em>carriage in neonates: the role of maternal carriage and phenotypic and molecular characteristics

Dominance of community-associated methicillin-resistant Staphylococcus aureus clones in a maternity hospital

Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates

Contact Info

Product

Resources

About