Abstract:Abstract:Infections of the central nervous system present the most significant challenge in our attempt to combat infectious diseases. Part of our inability to counter these diseases is attributed to an incomplete understanding of (i) how infectious agents cross the blood-brain barrier, a key step in the development of CNS infections, and (ii) the inability of drugs to traverse the blood-brain barrier to gain entry into the brain to kill parasites. Thus, there is an urgent need to expedite both drug discovery … Show more
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