2023
DOI: 10.1002/brb3.3334
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Non‐lesional white matter in relapsing–remitting multiple sclerosis assessed by multicomponent T2 relaxation

Pietro Bontempi,
Umberto Rozzanigo,
Sabrina Marangoni
et al.

Abstract: IntroductionThe purpose of the study is to investigate, by T2 relaxation, non‐lesional white matter (WM) in relapsing–remitting (RR) multiple sclerosis (MS).MethodsTwenty stable RR MS patients underwent 1.5T Magnetic Resonance Imaging (MRI) with 3D Fluid‐Attenuated Inversion‐Recovery (FLAIR), 3D‐T1‐weighted, and T2‐relaxation multi‐echo sequences. The Lesion Segmentation Tool processed FLAIR images to identify focal lesions (FLs), whereas T1 images were segmented to identify WM and FL sub‐volumes with T1 hypo‐… Show more

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