Non‐invasive ventilation: A glimpse into the future

Chu, Chung Ming; Piper, Amanda J.

doi:10.1111/resp.13710

Cited by 2 publications

(2 citation statements)

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“…Obese individuals had almost twice the odds of needing intubation and mechanical ventilation. NIV has also been increasingly reported to be responsible for favorable outcomes in all COPD patients regardless of BMI [ 21 , 22 ]. The higher rates of NIV and MV in COPD among obese individuals could be partly attributed to the co-existence of other pulmonary comorbidities, such as obstructive sleep apnea or obesity hypoventilation syndrome [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Impact of Obesity on In-Hospital Morbidity and Mortality Among Patients Admitted for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)

Bhide¹,

Bapaye²,

Mohan³

et al. 2023

Cureus

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BackgroundObesity has been considered to be a risk factor for increased morbidity and mortality among patients with cardiopulmonary diseases. The burden of chronic obstructive pulmonary disease (COPD) and obesity is very high in the United States. We aimed to use the National Inpatient Sample (NIS) to evaluate the impact of obesity on the outcomes of patients hospitalized with COPD exacerbation. Materials & MethodsThis is a retrospective cohort study from the NIS database involving adult patients hospitalized for COPD exacerbation in the year 2019 obtained using the international classification of diseases, 10 th revision coding system (ICD-10). Obese and morbidly obese subgroups were identified. Statistical analyses were done using the Stata software, and regression analysis was performed to calculate odds ratios. Adjusted odds ratios (aOR) were calculated after adjusting for potential confounders. ResultsAmong patients hospitalized for COPD exacerbations, mortality rates were lower among obese and morbidly obese patients; aOR 0.72 [0.65, 0.80] and aOR 0.88 [0.77-0.99], respectively. Obese and morbidly obese were more likely to require non-invasive ventilation aOR 1.63 [1.55, 1.7] and aOR 1.93 [1.85-2.05], respectively, and were more likely to require mechanical ventilation aOR 1. 25 [1.19, 1.31], and aOR 1.53 [1.44-1.62], respectively. The tracheostomy rate was 1.17%, 0.83%, and 0.38% among patients with morbid obesity, obesity, and nonobese patients, respectively. Obese ) and morbidly obese patients ) had higher odds of being discharged on home oxygen and to a skilled nursing facility (SNF), aOR , respectively. Average hospital charges and length of hospitalization were significantly higher for morbidly obese and obese patients as compared to non-obese patients (p < 0.01). ConclusionsAmong admissions for COPD exacerbation, the rates of non-invasive ventilation, mechanical ventilation, tracheostomy, discharge with supplemental oxygen, length of hospitalization, hospitalization charges, and discharge to an SNF were higher among obese patients representing a higher morbidity and healthcare utilization in this group. This, however, did not translate into increased mortality among obese patients admitted with COPD exacerbations, and further randomized controlled trials are required to confirm our findings.

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Section: Discussionmentioning

confidence: 99%

Impact of Obesity on In-Hospital Morbidity and Mortality Among Patients Admitted for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)

Bhide¹,

Bapaye²,

Mohan³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…A recent study examined the role of NIV technology with an automatically adjusting expiratory PAP algorithm (auto‐EPAP) on a single night in chronic respiratory failure patients with established coexisting OSA and found satisfactory results using this technology . Clearly, additional longer term studies looking at hard outcomes are needed before adoption of new technologies can be strongly recommended . Research on such technologies is, however, always challenged by both the wide range of devices and settings available.…”

Section: Non‐invasive Ventilationmentioning

confidence: 99%