Non-invasive optical and laboratory hematologic biomarkers correlate in patients with sickle cell disease
Timothy Quang,
Golnar Mostashari,
Elise Berning
et al.
Abstract:The goal of this study is to identify non-invasive optical hemodynamic biomarkers that can index laboratory hematology measurements in sickle cell disease (SCD). We acquired frequency-domain NIRS (FD-NIRS) and diffuse correlation spectroscopy (DCS) data from the forearms and foreheads of 17 participants in a randomized, double-blind, placebo-controlled trial evaluating effects of isoquercetin (IQ) on thromboinflammation in SCD. We observed multiple, significant correlations between optical and hematology bioma… Show more
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