Non-invasive Monitoring of Oxygen Delivery

Hoffman, George M.; Ghanayem, Nancy S.; Tweddell, James S.

doi:10.1007/978-1-4471-4619-3_105

Cited by 2 publications

(2 citation statements)

References 88 publications

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“…Estimates of regional and whole-body blood flow can be derived by application of the Fick principle using the arterioregional rSO 2 difference. Attention to this concept is important to clinical interpretation of NIRS-estimated or directly measured venous saturations [10,31]. The NIRS-derived arterioregional differences in the survivors in this cohort were close to those reported in normal newborns [32].…”

Section: Commentsupporting

confidence: 66%

Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome

Hoffman

Ghanayem

Scott

et al. 2017

The Annals of Thoracic Surgery

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Continuous noninvasive measurement of regional cerebral and somatic NIRS saturations in the early postoperative period can predict outcomes of early mortality and extracorporeal membrane oxygenation use in hypoplastic left heart syndrome. Because outcomes were strongly determined by NIRS measures at 6 hours, early postoperative NIRS measures may be rational targets for goal-directed interventions.

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Section: Commentsupporting

confidence: 66%

Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome

Hoffman

Ghanayem

Scott

et al. 2017

The Annals of Thoracic Surgery

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“…Physiologically, StO 2 is a measure of a combination of oxygen saturation in venous, arterial, and capillary blood. Thus, StO 2 is dependent on the regional delivery and consumption of oxygen in the tissues [ 20 , 21 ]. While US may be operator dependent and assesses function at the time of the intervention, it remains the current gold standard to directly visualize motility.…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Near-Infrared Spectroscopy and Transabdominal Ultrasonography: Noninvasive Monitoring of Intestinal Function in Neonates

et al. 2016

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BackgroundNear-infrared spectroscopy (NIRS) has the potential to continuously and noninvasively monitor intestinal function. This technology may be valuable because among neonates, intestinal maturity is highly variable and difficult to assess based solely on clinical signs. The aim of this study was to determine if there is an association between NIRS-based StO2 measurements and peristaltic activity assessed by transabdominal ultrasonography (US).Material/MethodsNineteen neonates of gestational age >32 weeks were categorized according to “no/low” versus “normal/hyperactive” motility levels, based on blinded US scan results. StO2 was recorded every 2 s for 24 h, following the ultrasound recording. Differences between the resulting estimates of average StO2 (bias of fits) and goodness-of-fit (residuals) were evaluated.ResultsNewborns with normal/hyperactive motility had higher mean StO2 than newborns with no/low motility (72.3±4.4 vs. 65.5±7.9, p<0.05, F=5.65). Residual errors were not significantly different between the 2 groups (p=0.213, F=0.213). A multivariate linear regression model using the means, residuals, and pairwise products of both, demonstrated more significant separation (0.47±0.26 vs. −0.24±0.33, p<0.01, F=27.4). A non-linear variant of the multivariate linear regression model demonstrated greatest separation (0.68±0.24 vs. −0.49±0.53, p<0.01, F=41.9).ConclusionsThis is the first study to demonstrate an association between NIRS-based StO2 measurements and peristaltic activity visualized by ultrasound imaging. NIRS may offer a continuous, noninvasive method to assess motility. This may have significant implications in premature infants at risk for feeding intolerance or necrotizing enterocolitis.

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Non-invasive Monitoring of Oxygen Delivery

Cited by 2 publications

References 88 publications

Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome

Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome

Relationship Between Near-Infrared Spectroscopy and Transabdominal Ultrasonography: Noninvasive Monitoring of Intestinal Function in Neonates

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