Non-invasive iron deficiency diagnosis: a saliva-based approach using capillary flow microfluidics

Prakobdi, Chirapha; Baldo, Thaisa A.; Aryal, Prakash; Link, Jeremy; Saetear, Phoonthawee; Henry, Charles S.

doi:10.1039/d3ay01933k

Anal. Methods

2024

DOI: 10.1039/d3ay01933k

|View full text |Cite

Non-invasive iron deficiency diagnosis: a saliva-based approach using capillary flow microfluidics

Chirapha Prakobdi,

Thaisa A. Baldo,

Prakash Aryal

et al.

Abstract: Capillary flow-driven microfluidic device as a viable non-invasive diagnostic tool for iron deficiency anemia (IDA) using saliva.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 31 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Comparative Analysis of Serum and Saliva Iron, Ferritin, and TIBC in Women with Iron Deficiency Anemia: Highlighting Saliva's Screening Potential

Farrokhnia,

Shoorgashti,

Sadeghian

et al. 2024

Middle East J Rehabil Health Stud

View full text Add to dashboard Cite

Background: Iron deficiency anemia is a prevalent form of anemia, particularly among women. Diagnosing and tracking this condition typically requires various measurements of serum iron, ferritin, and total iron-binding capacity (TIBC) through blood testing. Objectives: This study aims to evaluate the utility of saliva as a predictive marker for monitoring iron levels in iron deficiency anemia by comparing and correlating iron, ferritin, and TIBC levels in the serum and saliva of anemic and healthy women. Methods: In this comparative analysis, 40 women aged 20 - 40 with a similar periodontal status (anemic subjects = 20 and healthy subjects = 20) were examined. After a complete hematological and oral examination, salivary samples were collected using the spitting method, and iron, ferritin, and TIBC levels were measured and compared to the serum levels. Data were analyzed using SPSS 24. Results: The study results showed that the differences in saliva iron and ferritin levels were insignificant between the two groups (P-value = 0.07 and 0.26, respectively), but they were statistically significant in the serum (P-value = 0.0001 and 0.0001, respectively). Additionally, a significant difference was found in the saliva TIBC level (P-value = 0.001), which was negligible in the serum (P-value = 0.118). Conclusions: The results underscore the efficacy of integrating both serum and saliva analyses for comprehending iron-related parameters. While saliva analysis cannot entirely substitute for serum analysis, it represents a convenient approach that may serve as an initial step or be employed in large-scale anemia screenings.

show abstract

Comparative Analysis of Serum and Saliva Iron, Ferritin, and TIBC in Women with Iron Deficiency Anemia: Highlighting Saliva's Screening Potential

Farrokhnia,

Shoorgashti,

Sadeghian

et al. 2024

Middle East J Rehabil Health Stud

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Non-invasive iron deficiency diagnosis: a saliva-based approach using capillary flow microfluidics

Abstract: Capillary flow-driven microfluidic device as a viable non-invasive diagnostic tool for iron deficiency anemia (IDA) using saliva.

Cited by 1 publication

References 31 publications

Comparative Analysis of Serum and Saliva Iron, Ferritin, and TIBC in Women with Iron Deficiency Anemia: Highlighting Saliva's Screening Potential

Comparative Analysis of Serum and Saliva Iron, Ferritin, and TIBC in Women with Iron Deficiency Anemia: Highlighting Saliva's Screening Potential

Contact Info

Product

Resources

About