Non-invasive Intradermal Delivery of Hyaluronic Acid <i>via</i> Iontophoresis
Shinya Inoue,
Yasufumi Oshima,
Kentaro Kogure
Abstract:Hyaluronic acid (HA) is a hydrophilic supra-macromolecule, with a molecular weight (MW) 1000000<. HA is recognized as a biomaterial for skin moisturization. HA solution is typically injected into the skin using a needle. However, needle injection is invasive and does not result in homogeneous distribution of HA over a large area of skin. Therefore, non-invasive and effective technologies for homogenous intradermal delivery of HA are needed. Recently, we demonstrated the use of iontophoresis (ItP) for non-invas… Show more
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