Non-invasive estimation of human left ventricular end-diastolic pressure

Honda, Hiroaki; Nakaya, S; Kamada, Hiroki; Hasegawa, Hideyuki; Demachi, Jun; Chikama, Hisao; Sugimura, Koushirou; Yamamoto, Yorimasa; Kumasaka, Norihisa; Takita, Tamotsu; Ikeda, Jun; Kanai, Hiroshi; Koiwa, Yoshiro; Shirato, Kunio

doi:10.1016/s1350-4533(98)00029-0

Cited by 7 publications

(3 citation statements)

References 3 publications

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“…Due to the lack of in vivo pressure data in this study, pressure loading constraints were taken from other studies. To simulate diastolic filling, 1 kPa [7] was applied to the LV endocardial surface of the reference FE model.…”

Section: Diastolic Mechanics and Passive Stiffnessmentioning

confidence: 99%

Unsupervised segmentation and personalised FE modelling of in vivo human myocardial mechanics based on an MRI atlas

Wang

Hoogendoorn

Engelbrecht

et al. 2012

2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)

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We have developed techniques to automatically generate personalised biomechanical models of patients' hearts based on 3D cardiac images. We demonstrate this approach using multi-slice computed tomography images. Unsupervised segmentation was performed using non-rigid image registration with a segmented image. A finite element model was automatically fitted to the segmented data of the left ventricle. Passive and contractile myocardial mechanical properties were tuned to match the segmented surface geometries at end-diastole and end-systole, respectively. Global and regional indices of myocardial mechanics, including cardiac wall and myofibre strain distributions, were then quantified. This automated biomechanical modelling approach to cardiac image analysis provided noninvasive methods to characterise heart function, and may provide new quantitative diagnostic markers for heart failure.

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Section: Diastolic Mechanics and Passive Stiffnessmentioning

confidence: 99%

Unsupervised segmentation and personalised FE modelling of in vivo human myocardial mechanics based on an MRI atlas

Wang

Hoogendoorn

Engelbrecht

et al. 2012

2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)

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“…Thus, diagnosing a decline in heart performance could be critical for preventing heart problems. To understand heart performance, mechanical factors describing heart dynamics such as heart elastic stiffness, intracardiac pressure, and heart systolic force need to be considered, and past studies have intensively attempted to measure these quantities including pressure drop in valve stenosis, [1][2][3][4] absolute intracardiac pressure, [5][6][7] and elastic stiffness of heart tissues. [8][9][10][11][12] However, most of these quantities are still difficult to accurately measure at the practical level.…”

Section: Introductionmentioning

confidence: 99%

Physical Considerations on Bernoulli's Law for Mitral Valve Regurgitation

Tanaka¹,

Hashiba²

2010

Jpn. J. Appl. Phys.

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The simplified Bernoulli's equation is widely used in cardiology to measure the pressure difference between the left ventricle (LV) and the left atrium (LA). Even though this is a standard method, its derivation has not been well-clarified physically, which may lead to inappropriate usage of the method. In this study, derivation of the simplified Bernoulli's equation is presented with five assumptions: incompressible, irrotational, steady-state, negligible LV–LA height difference, and LA open space. Each assumption is analytically and numerically discussed as quantitatively as possible. We found that three factors, the LA size, the measurement location of regurgitation velocity, and the patient position in measuring regurgitation, need to be considered for appropriate usage of the simplified Bernoulli's equation.

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“…In particular, knowledge of the LV end-diastolic pressure (EDP), P ED , is usually needed to assess LV functioning in clinical settings; a noninvasive method to measure this was previously presented [1]. The eigenfrequency was found by using a short-time Fourier transform to the velocity signal on the human heart wall [2] which is measured transcutaneously in vivo by the phased tracking method [3] using ultrasound. However, the LV EDP, the normal value of which lies between 5 and 12mmHg, cannot be obtained from the blood pressure measured at the brachial artery.…”

mentioning

confidence: 99%

Noninvasive estimation of left-ventricular end-diastole elasticity by analysing heart wall vibrations

et al. 1999

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A new noninvasive method was previously presented for the measurement of the left ventricular (LV) end-diastolic pressure (EDP) by combining Mirsky's method and the experimentally derived relationship. The eigenfrequency was determined by applying a short-time Fourier transform to the velocity signal on the human heart wall which is transcutaneously measured in vivo by the phased tracking method using ultrasound. In the Letter the authors estimate the elasticity of the heart wall for several human patients.

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Non-invasive estimation of human left ventricular end-diastolic pressure

Cited by 7 publications

References 3 publications

Unsupervised segmentation and personalised FE modelling of in vivo human myocardial mechanics based on an MRI atlas

Unsupervised segmentation and personalised FE modelling of in vivo human myocardial mechanics based on an MRI atlas

Physical Considerations on Bernoulli's Law for Mitral Valve Regurgitation

Noninvasive estimation of left-ventricular end-diastole elasticity by analysing heart wall vibrations

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