Non-invasive brain stimulation for treatment of severe disorders of consciousness in people with acquired brain injury

Krewer, Carmen; Thibaut, Aurore

doi:10.1002/14651858.cd013533

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…The use of NIBS in clinical practice is continuously developing, and its role and position in neurological rehabilitation have become increasingly prominent. Combined with adjunctive exercises, the application of NIBS has been extrapolated from the treatment of post-stroke motor dysfunction to sensory disorders, aphasia, dysphagia, unilateral neglect, cognitive dysfunction, depression, and even disorders of consciousness in the acute phase [ 106 ].…”

Section: Overview Of Neuromodulation and Nibsmentioning

confidence: 99%

Noninvasive Brain Stimulation for Neurorehabilitation in Post-Stroke Patients

Zhou

et al. 2023

Brain Sciences

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Characterized by high morbidity, mortality, and disability, stroke usually causes symptoms of cerebral hypoxia due to a sudden blockage or rupture of brain vessels, and it seriously threatens human life and health. Rehabilitation is the essential treatment for post-stroke patients suffering from functional impairments, through which hemiparesis, aphasia, dysphagia, unilateral neglect, depression, and cognitive dysfunction can be restored to various degrees. Noninvasive brain stimulation (NIBS) is a popular neuromodulatory technology of rehabilitation focusing on the local cerebral cortex, which can improve clinical functions by regulating the excitability of corresponding neurons. Increasing evidence has been obtained from the clinical application of NIBS, especially repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). However, without a standardized protocol, existing studies on NIBS show a wide variation in terms of stimulation site, frequency, intensity, dosage, and other parameters. Its application for neurorehabilitation in post-stroke patients is still limited. With advances in neuronavigation technologies, functional near-infrared spectroscopy, and functional MRI, specific brain regions can be precisely located for stimulation. On the basis of our further understanding on neural circuits, neuromodulation in post-stroke rehabilitation has also evolved from single-target stimulation to co-stimulation of two or more targets, even circuits and the network. The present study aims to review the findings of current research, discuss future directions of NIBS application, and finally promote the use of NIBS in post-stroke rehabilitation.

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Section: Overview Of Neuromodulation and Nibsmentioning

confidence: 99%