Non-invasive brain stimulation for osteoarthritis

Zhu, Hui-Qi; Luo, Jing; Wang, Xueqiang; Zhang, Xinan

doi:10.3389/fnagi.2022.987732

Cited by 3 publications

(2 citation statements)

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“…Scalp stimulation was a non‐pharmacological treatment approach that precisely regulated cortical excitability and rhythms within specific brain regions 11 . It was considered a promising therapeutic approach for improving cognitive function and activities of daily living in patients with PSCID 12 .…”

Section: Introductionmentioning

confidence: 99%

“…Scalp stimulation was a non-pharmacological treatment approach that precisely regulated cortical excitability and rhythms within specific brain regions. 11 It was considered a promising therapeutic approach for improving cognitive function and activities of daily living in patients with PSCID. 12 Stimulus techniques commonly used to treat PSCID included scalp electroacupuncture (EA), 13 transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), and its spaced version theta burst stimulation (TBS), 14 as well as fastigial nucleus stimulation (FNS), 15 and others.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of scalp stimulation for multidomain cognitive impairment in patients with post‐stroke cognitive impairment and dementia: A network meta‐analysis and meta‐regression of moderators

Xu,

Li,

Zhang

et al. 2023

J Evidence Based Medicine

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BackgroundScalp stimulation has gained more traction for post‐stroke cognitive impairment and dementia (PSCID); the interaction between stimulation targets and parameters influences the response to the stimulation. However, the most efficacious treatment for improving different domains of cognitive impairment remains unknown.ObjectiveWe aimed to conduct a systematic review and network meta‐analysis (NMA) to compare the efficacy of various scalp stimulation protocols used in PSCID treatment.MethodsRandomized controlled trials of scalp stimulation in patients with PSCID were searched in eight databases over the past 20 years. Standardized mean differences (SMDs) for global and subdomain cognitive scores were pooled in Bayesian NMA. Moderators were examined using meta‐regression analysis.ResultsA total of 90 trials, with 6199 patients, were included. Low‐frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected dorsolateral prefrontal cortex (DLPFC) was highly suggested for alleviating global severity (SMD = 1.11, 95% CI (0.64, 1.57)). High‐frequency rTMS over the left DLPFC was recommended for language use (1.85 (1.18, 2.52)), executive function (0.85 (0.36, 1.33)), orientation deficits (0.59 (0.07, 1.13)), and attention (0.85 (0.27, 1.43)). Anodal transcranial direct current stimulation over the affected DLPFC (2.03 (0.72, 3.34)) was recommended for treating memory impairment. Meta‐regression analyses showed significant associations within attention, language and orientation.ConclusionOverall, different cognitive domains have different optimal scalp stimulation prescriptions, and activating the affected key brain regions and inhibiting the unaffected area is still the most effective treatment.

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Section: Introductionmentioning

confidence: 99%