Non-invasive biomarkers of disease activity and organ damage in ANCA-associated vasculitis: a systematic review
Thomas Renson,
Margaret M Kelly,
Hallgrimur Benediktsson
et al.
Abstract:BackgroundIn anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), histopathological assessment of affected tissue is often necessary for diagnosis and assessment of disease extent. There is a requirement for validated non-invasive biomarkers to avoid the need for serial tissue biopsies.MethodsA systematic review of scientific databases from 2012 until present was performed to identify studies fulfilling the inclusion criteria. Studies were assessed for quality using the Strengthening the Re… Show more
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