Non-invasive Biodiversified Sensors: A Modernized Screening Technology for Cancer

Takke, Anjali; Shende, Pravin

doi:10.2174/1381612825666191022162232

Cited by 13 publications

(8 citation statements)

References 124 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Biosensors have greatly changed the way diseases are diagnosed by allowing early-stage diagnosis when specific disease biomarkers first appear. Biosensors enable the sensitive and specific detection of disease markers with only a small number of samples (Takke and Shende, 2019). A typical biosensor configuration consists of three parts: a bioreceptor (e.g., an enzyme, antibody, or lipid) that is responsible for the selectivity of the device; a transducer that translates the physical or chemical change into a signal; and a signal output unit (Fitzgerald and Fenniri, 2017;Pasinszki et al, 2017;Takke and Shende, 2019).…”

Section: Cutting-edge Methods For Non-invasive Disease Diagnosis Usinmentioning

confidence: 99%

“…Biosensors enable the sensitive and specific detection of disease markers with only a small number of samples (Takke and Shende, 2019). A typical biosensor configuration consists of three parts: a bioreceptor (e.g., an enzyme, antibody, or lipid) that is responsible for the selectivity of the device; a transducer that translates the physical or chemical change into a signal; and a signal output unit (Fitzgerald and Fenniri, 2017;Pasinszki et al, 2017;Takke and Shende, 2019). Mass biosensors, electrical biosensors, and optical biosensors have been used for non-invasive cancer screening (Fitzgerald and Fenniri, 2017).…”

Section: Cutting-edge Methods For Non-invasive Disease Diagnosis Usinmentioning

confidence: 99%

See 1 more Smart Citation

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

et al. 2021

View full text Add to dashboard Cite

In modern society, the incidence of cancer, inflammatory diseases, nervous system diseases, metabolic diseases, and cardiovascular diseases is on the rise. These diseases not only cause physical and mental suffering for patients, but also place an enormous burden on society. Early, non-invasive diagnosis of these diseases can reduce the physical and mental pain of patients and social stress. There is an urgent need for advanced materials and methods for non-invasive disease marker detection, large-scale disease screening, and early diagnosis. Biomimetic medical materials are synthetic materials designed to be biocompatible or biodegradable, then developed for use in the medical industry. In recent years, with the development of nanotechnology, a variety of biomimetic medical materials with advanced properties have been introduced. Biomimetic nanomaterials have made great progress in biosensing, bioimaging, and other fields. The latest advance of biomimetic nanomaterials in disease diagnosis has attracted tremendous interest. However, the application of biomimetic nanomaterials in disease diagnosis has not been reviewed. This review particularly focuses on the potential of biomimetic nanomaterials in non-invasive disease marker detection and disease diagnosis. The first part focuses on the properties and characteristics of different kinds of advanced biomimetic nanomaterials. In the second part, the recent cutting-edge methods using biosensors and bioimaging based on biomimetic nanomaterials for non-invasive disease diagnosis are reviewed. In addition, the existing problems and future development of biomimetic nanomaterials is briefly described in the third part. The application of biomimetic nanomaterials would provide a novel and promising diagnostic method for non-invasive disease marker detection, large-scale clinical screening, and diagnosis, promoting the exploitation of devices with better detection performance and the development of global clinical public health.

show abstract

Section: Cutting-edge Methods For Non-invasive Disease Diagnosis Usinmentioning

confidence: 99%

Section: Cutting-edge Methods For Non-invasive Disease Diagnosis Usinmentioning

confidence: 99%

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Modifications of surface characteristics, polymer biocompatibility and better drug loading capacity of nanocarriers provide the advantages of biosensors [ 42–45 ] in comparison with other implants. In case of nano‐biosensors, multifunctional in‐vivo therapies such as self‐powered triboelectric nanogenerators released the drug at the targeted site in response to the seizure attack.…”

Section: Nanotheranostic Strategies In Epilepsymentioning

confidence: 99%

Nanotheranostics in epilepsy: A perspective for multimodal diagnosis and strategic management

Shende

Trivedi

2021

Nano Select

Self Cite

View full text Add to dashboard Cite

Epilepsy is a common but a complex neurological disorder with limited practices for successful management due to the complicated neuronal network and lack of knowledge of epileptic pathophysiology. Theranostic systems such as implantable devices and biodegradable nanomaterials offer better tailor‐made methods for the detection and treatment using nanotechnology‐based approaches for patients with epilepsy. Miniaturized nano‐implantable devices and biosensors equipped with operations to mimic neurostimulation demonstrate excellent opportunities in profiling the disease and assist in comprehension of the relationship between the disease and host. This strategy is developed for diagnoses and mapping brain activities to integrate and target therapeutic nanosystems in epilepsy. Non‐invasive class of nanotheranostics such as biodegradable and stimuli‐responsive polymers includes nanomaterials that utilize bio‐physico‐chemical processes or stimuli as a source for detecting the state and progress of the disease. The superior form of nanotheranostics encompasses in‐situ diagnostics with triggered release at the specific site. This review article focuses on the nanotheranostic strategies for epilepsy, their implications, challenges and new potentials for detection and therapy in personalized medicine. The concept of “on‐demand” release of drugs at the site of action using bio‐responsive theranostic approach reveals a potential for developing a point of primary care for epilepsy in the future.

show abstract

“…41,43,45−47 Such technologies have been the object of recent researches in the analysis, investigation, and monitoring of diseases such as breast, skin, and lung cancer. 48,49 Aimed at contributing to the woman's health, Rahman and collaborators 50 developed a wearable sensor for early breast cancer detection using an organic flexible substrate based on 5-(4-(perfluorohexyl)phenyl)thiophene-2-carbaldehyde with two antennas for microwave imaging through electromagnetic performance analysis, which facilitates the implantation into a bra. The system for imaging was made using a bistatic radar that consists of two omnidirectional antennas operated at frequencies between 4 and 6 GHz.…”

Section: Clinical Applicationsmentioning

confidence: 99%

Wearable and Biodegradable Sensors for Clinical and Environmental Applications

Baldo

Lima

Mendes

et al. 2020

ACS Appl. Electron. Mater.

View full text Add to dashboard Cite

This current Review focuses on recent contributions of wearable and biodegradable sensors dedicated to health and environmental applications. Recent examples reported in the literature are presented and critically discussed in order to diagnose diseases and their response to treatment with a focus on cancer and Parkinson’s disease. Advances in devices for body temperature, humidity (skin hydration), human physiological signals, and metal detection in body fluids are demonstrated concerning simple and portable platforms. Studies performed outside the controlled laboratory environment can rapidly help in point-of-care analyses or self-examination by the patients. Environmental approaches are also outlined, aiming at gas detection, metal sensing, and environment humidity, including different substrates showing not only flexible and biodegradable sensors but also wireless detection and data communication. The discussed examples for health and environmental analyses have successfully demonstrated the considerable potential of wearable devices for real-time and on-site applications, highlighting the self-monitoring capacity. Future investigations should consider the device’s operational simplicity with a more straightforward interpretation of results to make them affordable for the market. The huge potential of wearable and biodegradable devices enables them as emerging and powerful platforms for replacing current gold standard methods for rapid health screening and environmental monitoring in the near future. The next trend in the technological field of the development and application of new biodegradable materials to wearable devices should focus on studies involving the stability, toxicity, and biocompatibility of the final devices.

show abstract

Non-invasive Biodiversified Sensors: A Modernized Screening Technology for Cancer

Cited by 13 publications

References 124 publications

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

Nanotheranostics in epilepsy: A perspective for multimodal diagnosis and strategic management

Wearable and Biodegradable Sensors for Clinical and Environmental Applications

Contact Info

Product

Resources

About