2018
DOI: 10.1530/ey.15.15.8
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Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

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Cited by 6 publications
(18 citation statements)
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“…These important results advocate for high dose LT4 treatment without adverse effects in adult life in accordance with a recent study from New Zealand 2 and the current ESPE guidelines. Concerns raised recently concerning worse intellectual outcome in CH patients at the age of 11 years after episodes of overtreatment during the first two years of life 3 were not confirmed in this study. Newborn screening (NBS) is an invaluable tool for identification of CH; however almost 70% of newborns worldwide do not benefit from NBS at all.…”
Section: Mean High-dose L-thyroxine Treatment Is Efficient and Safe Tcontrasting
confidence: 99%
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“…These important results advocate for high dose LT4 treatment without adverse effects in adult life in accordance with a recent study from New Zealand 2 and the current ESPE guidelines. Concerns raised recently concerning worse intellectual outcome in CH patients at the age of 11 years after episodes of overtreatment during the first two years of life 3 were not confirmed in this study. Newborn screening (NBS) is an invaluable tool for identification of CH; however almost 70% of newborns worldwide do not benefit from NBS at all.…”
Section: Mean High-dose L-thyroxine Treatment Is Efficient and Safe Tcontrasting
confidence: 99%
“…This study sheds light on the long-term efficacy of GH treatment in PWS children by analysing data collected in the largest available international database. Although GH therapy was far less effective in stimulating growth than in non-PWS GHD subjects, these results confirm the effectiveness of this treatment in children with PWS leading to an average final height of −1.2 SDS, corresponding to 170 cm in males and 156 cm in girls, consistent with previous studies performed in smaller numbers [2][3][4]. GH was effective not only in increasing height but also in controlling the progression of obesity.…”
Section: Growth Hormone Treatment In Children With Prader-willi Syndrsupporting
confidence: 88%
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