Non‐grafted sinus implants in periodontally compromised patients: a time‐to‐event analysis

Abstract

This study reports the results of implant therapy involving a sinus membrane lift and of conventional implant therapy in 68 periodontally compromised patients treated between June 1990 and June 2002. Patients had at least two implants inserted, one of which was placed in the maxillary sinus region following fenestration of the lateral sinus wall and lifting of the sinus membrane. Two implant systems were used: a two-stage system (Astra) and a one-stage system (ITI). Annual follow-up visits included recording of plaque, probing pocket depth and measurement of the radiographic distance in millimeter from the implant shoulder to the alveolar crest. Survival analysis showed that the proportion of implants that had not been explanted after 5 years ranged between 88.7% for ITI sinus implants and 97% for ASTRA conventional implants. After 10 years, the proportion of implants remaining in situ ranged between 59% for ITI conventional implants and 97% for ASTRA conventional implants. Cox regression analyses showed that the factors influential for implant explantation were implant type (HR(ITI) = 2.8), implant length (HR(< or = 10 mm) = 3.1), patient being a smoker (HR(smoking) = 2.2) and patient having at least 20 natural teeth (HR(> or = 20 teeth) = 3.8). Our results demonstrate that sinus implants may be inserted with the same success as conventional implants in periodontally compromised patients.

Characterization of human ethmoid sinus mucosa derived mesenchymal stem cells (hESMSCs) and the application of hESMSCs cell sheets in bone regeneration

“…Cells derived from different sources have different characteristics [3], so in an effort to foster a more uniform characterization of MSC across different tissue sources and various culture conditions, the International Society for Cellular Therapy (ISCT) has proposed a set of minimal criteria to define MSCs [31,51,52]. In the present study, the surface marker expression of hESMSCs was shown to be in conformity with the criteria mentioned above.…”

“…In bone tissue engineering, cell sheets could act as periosteum, which can provide osteoprogenitor cells and nutrients to the bone defect, thus contributing to regeneration of the host tissue [30]. In the meantime, a clinical study showed that the maxillary sinus lifting resulted in bone augmentation, suggesting that the sinus membrane may function like a periosteum [31]. Although mucosa of both ethmoid sinus and maxillary sinus are sources of cells of osteogenic differentiation potential [10,32], cells from ES have higher colony-forming potential and proliferation capability than cells from MS [10].…”

The innate osteogenic potential of the maxillary sinus (Schneiderian) membrane: an ectopic tissue transplant model simulating sinus lifting

“…The native osteogenic activity associated with the Schneiderian membrane shown by these experiments correlates well with clinical observations of bone formation in sinus lifting procedures without grafting bone substitutes 10,26 . Several studies have shown that mechanical stimulation of the periosteum can also elicit the latent osteogenic capacity of the periosteum in various clinical settings 16,17,28,32 and recently in calvaria and in mandibular periostea in minipigs and in rabbits, respectively 6,20 .…”

“…The most commonly used technique to reconstruct the posterior region of the maxilla is augmentation of the maxillary sinus floor, a technique introduced by BOYNE & JAMES and modified by TATUM and by WOOD & MOORE, in which different osteoconductive materials (bone substitutes) were placed between the host bone and the sinus membrane to allow the insertion of dental implants 4,33,36 . Recent clinical studies described a surgical technique combining an open controlled sinus membrane lifting procedure with immediate installation of dental implants that resulted in bone formation only by simple elevation of the maxillary Schneiderian sinus membrane (MSSM) without any adjunctive graft materials 9,10,16,17,22,26,28,32,35,36 .…”

Le sevrage tabagique par les dentistes et stomatologues

“…Actualités Odonto-Stomatologiques n°237, mars 2007 dents de sagesse [2] ou de la pose d'implants [3,4] . La consolidation osseuse est particulièrement concernée et se fait trois fois plus souvent avec retard.…”