Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Colombo, Nicoletta; Peiretti, Michele; Garbi, Annalisa; Carinelli, Silvestro; Marini, Carolina; Sessa, C.

doi:10.1093/annonc/mds223

Cited by 158 publications

(100 citation statements)

References 23 publications

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“…They have different biological behaviors with a variety of histopathological subtypes; in addition, they have curative potential with different treatment approaches compared with much more commonly encountered epithelian ovarian cancers (Quirk and Natarajan, 2005;Young, 2005;Ayhan et al, 2009;Koulouris and Penson, 2009;Colombo et al, 2012;Penson, 2013;Takeuchi et al, 2013). The cure rates of early stage GCTs approach 100%, and even in the advanced stage of the disease, surgery and the BEP regimen result in cure rates of approximately 75% (Gershenson, 2007;Parkinson et al, 2011;Matei et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…In ROTs, the clarification of prognostic factors that have an impact on survival is important for accurate diagnosis and treatment strategies, such as surgery, adjuvant treatment, and effective treatment of relapse (Garcia et al, 1999;Koulouris and Penson, 2009;Colombo et al, 2012). Because these tumors are rarely encountered in clinical practice, randomized clinical trials to evaluate the effects of proposed treatment regimens are limited in the literature.…”

Section: Introductionmentioning

confidence: 99%

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Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

Bılıcı

İnanç²,

Ulaş³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

Bılıcı

İnanç²,

Ulaş³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…The lab evoked the diagnosis of immature teratoma vs yolk salk tumor. Based on the results, we proceeded to a right adnexectomy with the infundibulopelvic ligament followed by omentectomy; even though there is no consensus for a systematic lymphadenectomy in germ cell tumors [9], bilateral iliac and paraaortic lymphadenectomy as well as appendectomy were performed. The operation was terminated by the washing of the peritoneal cavity and the placement of drainage.…”

Section: Discussionmentioning

confidence: 99%

“…Diagnosis is mainly based on imaging and secondary in blood tests. In young patients, human chorionic gonadotropin (HCG), α-fetoprotein (AFP) and lactate dehydrogenase (LDH), complete blood count, and liver and renal function tests should be carried out [9].…”

Section: Discussionmentioning

confidence: 99%

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Immature Ovarian Teratoma in a 21 Year –Old Woman: A Case Report and Review of the Literature.

Stavrou¹

2015

J Gen Pract

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with specific tumor markers .So, tumor markers Ca 15-3, Ca19-9, Ca 125, and CEA were fluctuated in normal ranges. Serum levels of alphafetoprotein (a-FP) were significantly elevated reaching the plateau of 392 iu/ ml (normal ranges: <9.5 iu/ml), supporting the sonographically evoked opinion of underlying malignancy. Except that AST (62 IU/L), ALT (73 IU/L) and LDH (309 IU/L) were mildly increased.Because of the young profile of the patient, MRI of upper and lower abdomen has been also performed; similarly to ultrasonographic report, MRI noticed the presence of excessive ascites; it also described a heterogeneous right ovarian mass of 88 × 81 × 100 mm presenting cystic, solid and hemorrhagic contents, fixed to the broad ligament of the uterus. It also revealed 2 thin walled cysts of 4, 3 cm and 2, 4 cm in the left ovary without solid parts. Intraperitoneal tissue in the region of upper abdomen was described, implying the possibility of underlying peritoneal carcinomatosis. The liver, the biliary system, the spleen, the pancreas and the adrenals were normal. MRI didn't reveal enlarged paraaortic, mesenteric, iliac or inguinal lymph nodes (Figure 2). Chest X-ray and ultrasonographically breast examination were normal. Initially, ascites suction was realized in order to alleviate from pressing symptoms. In the operation theater under general anesthesia, laparoscopy was performed with the technique of the four ports for better abdominal exploration in the overweight patient; 4 to 5 liters of ascites were aspirated for cytological examination. The organs of the upper abdomen were normal, without implantations in the peritoneum or omental disease. The uterus and the left adnexa were normal but a mass 10-12 cm of right ovary characterized by abnormal surface was revealed. So exploratory laparotomy followed with vertical incision .Then the cystic lesion was removed and sent for frozen section. The rapid biopsy was positive for

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Gyn Oncology

Straight

Bradford

Zweizig

2019

Cancer

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Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Cited by 158 publications

References 23 publications

Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

Immature Ovarian Teratoma in a 21 Year –Old Woman: A Case Report and Review of the Literature.

Gyn Oncology

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