Non-enzymatic electrochemical sensing of dopamine from COVID-19 quarantine person

Melamine-derived N-rich C-entrapped Au nanoparticles for sensitive and selective monitoring of dopamine in blood samples

“… 3 Even though these strategies had a significant effect in controlling the COVID-19 outbreak and helped reducing its transmission, they had a very strong negative impact on people's mental health. 4 It has been reported that various neurological disorders such as delirium, agitation, confusion, depression, anxiety, and traumatic stress symptoms appeared in quarantined, isolated, and even in COVID-19 survivors. 5 The appearance of these neurological disorders could be due to alteration in neurotransmitters.…”

Bioinspired NC Coated BM‐ZIF for Electrochemical Monitoring of Adrenaline from Blood and Pharmaceutical Samples

“…The COVID-19 pandemic has resulted in a massive loss of human life throughout the world [1], and it poses an unprecedented threat to public health, food systems, and the workplace [2]. The epidemic has wreaked havoc on the economy and society by putting more than ten millions of people at the danger of severe poverty [2,3].…”

“…The COVID-19 pandemic has resulted in a massive loss of human life throughout the world [1], and it poses an unprecedented threat to public health, food systems, and the workplace [2]. The epidemic has wreaked havoc on the economy and society by putting more than ten millions of people at the danger of severe poverty [2,3]. The COVID-19 pandemic not only impacted human health [4] by causing respiratory and digestive tract infection, acute respiratory distress syndrome, septic shock, or even systemic multiorgan failure syndrome [5], but it has also disrupted or halted the quarantined person's cognitive capabilities, eventually leading to delirium, agitation, sleeplessness, despair, hypertension, anxiety, and even stroke.…”

“…Adrenaline (AD), a catecholamine neurotransmitter has an important role in central and peripheral neuroendocrine to respond mental and physical stress [7]. Adrenaline is present in nanomolar concentrations in human serum, typically ranges between 10-1000 nML À 1 [2]. Any variation from normal range of AD may lead to Parkinson's, Schizophrenia, anxiety, sadness, hypertension, and even attention deficit hyperactivity disorder [8].…”

“…But, ZIFs have a microporous shape and poor conductivity, which restricts active site exposure and mass transfer. To meet above challenges, new strategies have been designed in which ZIFs are linked with a variety of different conductive materials including multiwall carbon nanotubes [28], conducting polymers [2], and nitrogen-carbon (NC) coated nanomaterials [29]. Among these, NC based nanomaterials offers high conductivity, ease of synthesis and modification, high temperature resistance, cheap cost, large specific surface area, chemical stability, potential to reduce electrode fouling, allowing for a rapid electron diffusion rate and enough interface contact between the modified electrode and the electrolyte and low background current [30].…”