Non-digestible galactomannan oligosaccharides from Cassia seed gum modulate microbiota composition and metabolites of human fecal inoculum

Evaluation of in vitro prebiotic effects of galactomannan oligosaccharides derived from guar gum

“…Compared to the control group, the abundance of Megasphaera (29.12%), Lactobacillus (9.68%), Bifidobacterium (2.35%), and Bacteroides (4.45%) increased in the GMOS group. In general, Lactobacillus and Bifidobacterium can be used as markers of intestinal health (Miao et al ., 2021). Studies suggest that Lactobacillus can ameliorate dyslipidaemia and produce lactic acid (Jiang et al ., 2022).…”

Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis

“…In humans, galactomannan ingestion has been related to glycemic index reduction in diabetics, alleviation of the irritable bowel syndrome symptoms, prebiotic effects, and improvement of short-chain fatty acid ( SCFA ) production ( Singh et al, 2018 ; Rao and Quartarone, 2019 ; Miao et al, 2021 ). However, in broilers, diets with high concentrations of plant-derived galactomannans are associated with poor performance, reduced feed intake, nutrient and lipid absorption, innate immune response stimulation, and excessive digesta viscosity ( Lee et al, 2003 ; Shirouchi et al, 2011 ; Shastak et al, 2015 ).…”