Non-COVID-19 Patients with Life-threatening Diseases Who Visited a Fever Clinic: A Single-center, Observational Study in Tokyo, Japan

Akiyama, Yutaro; Morioka, Shigefumi; Wakimoto, Yuji; Kawashima, Akira; Kanda, Kohei; Okuhama, Ayako; Suzuki, T.; Miyazato, Yusuke; Nomoto, Hidetoshi; Ide, Satoshi; Nakamoto, Takato; Nakamura, Keiji; M, Ota; Moriyama, Yuki; Takaya, Saho; Yamada, Kota; Taguchi, Maho; Sugito, Erika; Izuka, Shinji; Ishiguro, Kenji; Kobayashi, Toshiaki; Miyake, Wataru; Kubota, Shuji; Ishikane, Masahiro; Iwamoto, Noriko; Yamamoto, Kei; Ujiie, Mugen; Kutsuna, Satoshi; Hayakawa, Kayoko; Saito, Sho; Ohmagari, Norio

doi:10.2169/internalmedicine.5614-20

Cited by 4 publications

(6 citation statements)

References 5 publications

(5 reference statements)

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“…However, oral, pharyngeal and cervical infections (e.g., PA, tonsillitis, acute epiglottitis, deep neck abscess) may be overlooked if a thorough oral and pharyngo-laryngeal evaluation is avoided due to the high transmissibility of COVID-19. Akiyama et al ( 9 ) reported the necessity of careful evaluation for life-threatening diseases in cases with fever during the COVID-19 pandemic era.…”

Section: Discussionmentioning

confidence: 99%

“…The importance of using personal protective equipment and isolation to prevent exposure to aerosols containing SARS-CoV-2, as well as the restriction of transoral procedures to severe cases (e.g., airway obstruction) has been highlighted in the COVID-19 pandemic era ( 2 ). Although COVID-19 can be easily diagnosed with rapid tests, co-infection with life-threatening oral, pharyngeal and laryngeal infections may be underdiagnosed due to insufficient oral examination ( 9 ). These diseases should not be overlooked due to the lack of appropriate evaluation.…”

Section: Discussionmentioning

confidence: 99%

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COVID‑19 and peritonsillar abscess co‑infection: A case report

Tanaka

Mikami

Kimura

et al. 2022

Med Int

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Coronavirus disease 2019 (CoVID-19) generally presents with fever, shortness of breath and a sore throat. these symptoms are also common in oral and pharyngeal infections, such as peritonsillar abscess (Pa). the present study describes a case of Pa and CoVID-19 co-infection. although CoVID-19 was initially suspected in the patient due to the presenting symptoms of fever, sore throat, dysgeusia and dysosmia, an oral examination and computed tomography scan detected Pa. the patient was conservatively managed with intravenous antibiotics without transoral drainage of the abscess. anti-CoVID-19 medication was not administered as the CoVID-19 infection in the patient was not severe. laboratory findings revealed high levels of leukocytes, C-reactive protein (CrP) and procalcitonin. on the whole, the association between laboratory findings (including leukocyte count, CrP and procalcitonin levels) and bacterial co-infection with CoVID-19 remains unclear, and further studies are warranted. oral examinations and transoral procedures are often avoided due to the high risk of the aerosolisation of CoVID-19 viral particles. However, an appropriate evaluation is essential in order to avoid the underdiagnosis of life-threatening bacterial infections that co-exist with CoVID-19.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

COVID‑19 and peritonsillar abscess co‑infection: A case report

Tanaka

Mikami

Kimura

et al. 2022

Med Int

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“…On the final day of this lockdown, 16,820 COVID-19 related hospital deaths were recorded [ 7 ]. The pressure experienced by the healthcare system may have resulted in collateral damage with regard to other patients, particularly for those with serious or urgent diseases [ 1 , 8 ]. Moreover, many patients have been hesitant to seek healthcare, a phenomenon described in the literature regarding the severe acute respiratory syndrome (SARS) epidemics [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Impact on Stroke Admissions during France’s First Epidemic Peak: An Exhaustive, Nationwide, Observational Study

Risser¹,

Loc²,

Binder-Foucard³

et al. 2022

Cerebrovasc Dis

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Introduction: The coronavirus disease 2019 (COVID-19) pandemic continues to have great impacts on the care of non-COVID-19 patients. This was especially true during the first epidemic peak in France, which coincided with the national lockdown. The aim of this study was to identify whether a decrease in stroke admissions occurred in spring 2020, by analyzing the evolution of all stroke admissions in France from January 2019 to June 2020. Methods: We conducted a nationwide cohort study using the French national database of hospital admissions (Information Systems Medicalization Program) to extract exhaustive data on all hospitalizations in France with at least one stroke diagnosis between January 1, 2019, and June 30, 2020. The primary endpoint was the difference in the slope gradients of stroke hospitalizations between pre-epidemic, epidemic peak, and post-epidemic peak phases. Modeling was carried out using Bayesian techniques. Results: Stroke hospitalizations dropped from March 10, 2020 (slope gradient: −11.70), and began to rise again from March 22 (slope gradient: 2.090) to May 7. In total, there were 23,873 stroke admissions during the period March–April 2020, compared to 29,263 at the same period in 2019, representing a decrease of 18.42%. The percentage change was −15.63%, −25.19%, −18.62% for ischemic strokes, transient ischemic attacks, and hemorrhagic strokes, respectively. Discussion/Conclusion: Stroke hospitalizations in France experienced a decline during the first lockdown period, which cannot be explained by a sudden change in stroke incidence. This decline is therefore likely to be a direct, or indirect, result of the COVID-19 pandemic.

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“…8 A reduction in the quality and quantity of care as a result of the extreme pressure experienced by the healthcare system may have resulted in collateral damage with regard to other patients, particularly for those with serious or urgent diseases requiring immediate treatment. 1,9,10 In addition, many patients have been hesitant to seek heath care during this period, a phenomenon briefly described in the literature regarding the shorter SARS epidemics. 11,12 To date, several works have alerted to an unexpected decrease in hospital admissions for non COVID-19 diseases, but very few have estimated this on a national level.…”

Section: Introductionmentioning

confidence: 99%

“…The care of non-COVID patients has certainly been impacted as a result. [1][2][3][4] The capacity of healthcare systems worldwide was rapidly overwhelmed following the beginning of the pandemic. France faced a shortage of both medical supplies and human resources during the first epidemic peak, in spring 2020, despite undertaking 55 days of national lockdown (from 17 March to 10 May 2020 included) .…”

Section: Introductionmentioning

confidence: 99%

COVID-19 impact on stroke admissions during France’s first epidemic peak: an exhaustive, nationwide, observational study

Risser

Loc

Binder-Foucard

et al. 2021

Preprint

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Background and Purpose: The COVID-19 pandemic continues to have great impacts on the care of non-COVID-19 patients. This was especially true during the first epidemic peak in France, which coincided with the national lockdown (17 March 2020 to 10 May 2020). Patients with serious and urgent disease like stroke may have experienced a degradation of care, or may have been hesitant to seek healthcare during this period. The aim of this study was to identify, on a national level, whether a decrease in stroke admissions occurred in spring 2020, by analyzing the evolution of all stroke admissions in France from January 2019 to June 2020. Methods: We conducted a nationwide cohort study using the French national database of hospital admissions (PMSI) to extract exhaustive data on all hospitalizations in France with at least one stroke diagnosis between 1 January 2019 and 30 June 2020. The primary endpoint was the difference in the slope gradients of stroke hospitalizations between pre-epidemic, epidemic peak and post-epidemic periods. Modeling was carried out using Bayesian techniques. Results: Stroke hospitalizations dropped from 10 March 2020 (slope gradient: -11.70), and began to rise again from 22 March (slope gradient: 2.090) to 7 May. In total, there were 23 873 stroke admissions during the period March-April 2020, compared to 29 263 at the same period in 2019, representing a decrease of 18.42%. The percentage change was -15.63%, -25.19%, -18.62% for ischemic strokes, transient ischemic attacks, and hemorrhagic strokes, respectively. In spatial models of French departments, the incidence of COVID-19 explained the ratio of stroke hospitalizations. Conclusions: Stroke hospitalizations in France experienced a decline during the first lockdown period, which cannot be explained by a sudden change in stroke incidence. This decline is therefore likely to be a direct, or indirect, result of the COVID-19 pandemic.

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Non-COVID-19 Patients with Life-threatening Diseases Who Visited a Fever Clinic: A Single-center, Observational Study in Tokyo, Japan

Cited by 4 publications

References 5 publications

COVID‑19 and peritonsillar abscess co‑infection: A case report

COVID‑19 and peritonsillar abscess co‑infection: A case report

COVID-19 Impact on Stroke Admissions during France’s First Epidemic Peak: An Exhaustive, Nationwide, Observational Study

COVID-19 impact on stroke admissions during France’s first epidemic peak: an exhaustive, nationwide, observational study

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