Non-corticosteroid adjuvant therapies for acute bacterial meningitis

N2 Year in Review

“…73 Robust neuroinflammation is considered to be a major driver of the hearing loss associated with bacterial meningitis, and adjuvant corticosteroids (but not noncorticosteroid adjuvants) in combination with antibiotics have proved to reduce the risk of hearing loss and some other neurologic deficits in adults and children. [74][75][76] Predictive markers for neurologic outcomes, including cognitive impairment, in bacterial meningitis are clearly needed.…”