Non-contact quantification of tissue biomechanics during embryo development with Brillouin microscopy and optical coherence tomography (Conference Presentation)

Zhang, Jitao; Raghunathan, Raksha; Rippy, Justin; Wu, Chen; Finnell, Richard H.; Larin, Kirill V.; Scarcelli, Giuliano

doi:10.1117/12.2507554

Cited by 1 publication

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“…Dr. Jitao Zhang from the University of Maryland, USA, presented a collaboration work between Scarcelli-Larin and Finnell groups for noncontact quantification of tissue biomechanics during embryo development with Brillouin microscopy and OCT. 68 Embryonic development involves the interplay of driving forces that shape the tissue and the mechanical resistance that the tissue offers in response. However, quantifying the stiffness of tissue in situ with 3-D high resolution and in a noncontact manner has so far been difficult to achieve.…”

Section: Brillouin Elastographymentioning

confidence: 99%

Optical elastography and tissue biomechanics

2019

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Mechanical forces play an important role in the behavior and development of biological systems and disease at all spatial scales, from cells and their constituents to tissues and organs. Such forces have a profound influence on the health, structural integrity, and normal function of cells and organs. Accurate knowledge of cell and tissue biomechanical properties is essential to map the distribution of forces and mechanical cues in biological systems. Cell and tissue biomechanical properties are also known to be important on their own as indicators of health or disease states. Hence, optical elastography and biomechanics methods can aid in the understanding and clinical diagnosis of a wide variety of diseases. We provide a brief overview and highlight of the Optical Elastography and Tissue Biomechanics VI conference, which took place in San Francisco, February 2 and 3, 2019, as a part of Photonics West symposium.

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Section: Brillouin Elastographymentioning

confidence: 99%