Non-Coding RNAs in HIV Infection, NeuroHIV, and Related Comorbidities
Seema Singh,
Uma Maheswari Deshetty,
Sudipta Ray
et al.
Abstract:NeuroHIV affects approximately 30–60% of people living with HIV-1 (PLWH) and is characterized by varying degrees of cognitive impairments, presenting a multifaceted challenge, the underlying cause of which is chronic, low-level neuroinflammation. Such smoldering neuroinflammation is likely an outcome of lifelong reliance on antiretrovirals coupled with residual virus replication in the brains of PLWH. Despite advancements in antiretroviral therapeutics, our understanding of the molecular mechanism(s) driving i… Show more
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