Non-antibacterial alternative measures for urinary tract infection in children. Part 1. Suppression of the microbial initiation of the inflammation

Кириллов, В. И.; Богданова, Н. А.; Морозов, С. Л.

doi:10.21508/1027-4065-2018-63-1-106-112

Cited by 2 publications

(1 citation statement)

References 20 publications

(26 reference statements)

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“…At the same time, there is a high rate of recurrence -in 30-40 % of patients who underwent UTI [3]. The main pathogens of UTI in 80 % of cases are Escherichia coli and in 15 % of cases Proteus spp., Pseudomonas aeruginosa, Staphylococcus aureus, S. typhymurium, Enterococcus faecalis [4][5][6][7][8][9][10]. The basic drugs for the treatment of patients with UTI are antibiotics and uroantiseptics (derivatives of 8-oxyquinoline, 5-nitrofuran, etc.)…”

Section: Introductionmentioning

confidence: 99%

Study of Anti-Inflammatory Effect of Concentrated Juice and Granules From Vaccinium Oxycoccos Fruits on the Model of Bacterial Cystitis in Rats

Yatsyuk¹,

Fedorovska²,

Antymis³

2020

EUREKA: Health Sciences

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The fruits of marsh cranberries due to the content of phenolic compounds, in particular proanthocyanidins, are effective in the prevention and treatment of cystitis [1]. The aim of the research was to study the anti-inflammatory properties of condensed juice of Vaccinium oxycoccos fruits and granules “Cranberry” in a model of acute bacterial cystitis in rats. Materials and methods. The anti-inflammatory properties of condensed juice from Vaccinium oxycoccos fruits and granules “Cranberry” were studied in a model of acute bacterial cystitis in rats, which was caused by three daily transurethral injection into the bladder of 0.3 ml of E. coli strain at a concentration of 106 CFU/ml. “Canefron® H” was used as a reference drug. Tissues were studied histologically by assessing the structure of the bladder wall and the condition of blood vessels. Results. Infection of animals with E. coli resulted in a significant increase in the desquamation of the transitional epithelium, edematous changes and narrowing of blood vessels in the tissues of the bladder wall. During treatment with the drug “Canefron® N” there was a decrease in cell infiltration and desquamation of cells, dilation of blood vessels. When animals used condensed juice from Vaccinium oxycoccos fruits and granules “Cranberry” in the histological picture of the walls of the bladder there was a decrease in desquamation, edema and cellular infiltration, the lumen of blood vessels was approaching normal. Conclusions. The use of condensed juice from Vaccinium oxycoccos fruits and granules “Cranberry” was accompanied by a positive effect on the tissues of the walls and blood vessels of the bladder of rats (there was a decrease in desquamation of the superficial layers of the transitional epithelium and normalization of the histological picture of vascular entanglement, that was not inferior to the comparison drug “Canefron® N”.

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Section: Introductionmentioning

confidence: 99%

Study of Anti-Inflammatory Effect of Concentrated Juice and Granules From Vaccinium Oxycoccos Fruits on the Model of Bacterial Cystitis in Rats

Yatsyuk¹,

Fedorovska²,

Antymis³

2020

EUREKA: Health Sciences

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Genetic aspects of the development of congenital anomalies of the kidney and urinary tract

Kursova,

Morozov,

Baiko

et al. 2024

Ross. vestn. perinatol. pediatr.

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Congenital anomalies of the kidney and urinary tract (CAKUT) include a wide range of structural anomalies that develop as a result of impaired morphogenesis of the kidneys and/or urinary tract. CAKUT accounts for about 40–50% of patients under 21 with chronic kidney disease worldwide. Most congenital anomalies of the urinary system are diagnosed in utero or during the first months of a child’s life, which determines further tactics for managing a child, depending on the severity of CAKUT and the degree of decrease in the filtration function of the kidneys. The article provides modern data on the causes of the development of anomalies of the urinary system, provides examples of the development of scientific areas that will be aimed at predicting the occurrence of malformations. In addition, early markers of the disease are considered. Thus, the problem of anomalies of the urinary system remains relevant to the present despite the significant contribution of genetics to understanding the pathogenesis and predicting the development of CAKUT.

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Non-antibacterial alternative measures for urinary tract infection in children. Part 1. Suppression of the microbial initiation of the inflammation

Cited by 2 publications

References 20 publications

Study of Anti-Inflammatory Effect of Concentrated Juice and Granules From Vaccinium Oxycoccos Fruits on the Model of Bacterial Cystitis in Rats

Study of Anti-Inflammatory Effect of Concentrated Juice and Granules From Vaccinium Oxycoccos Fruits on the Model of Bacterial Cystitis in Rats

Genetic aspects of the development of congenital anomalies of the kidney and urinary tract

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