Non-anastomotic Biliary Strictures Following Orthotopic Liver Transplantation: Treatment with Percutaneous Transhepatic Biliary Drainage

Lu, Ningning; Huang, Qiang; Wang, Jianfeng; Baojie, Wei; Gao, Kun; Zhai, Rihong

doi:10.5754/hge12300

Cited by 2 publications

(2 citation statements)

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“…As a last resort in non-responders, endoscopic therapy may also serve as a bridge to retransplantation 89. PTBD insertion has similar efficacy as endoscopic management for NAS, but complications such as drain malfunctions and patient discomfort preclude its use unless endoscopic management fails, in altered surgical anatomy or peripheral lesions not amenable to endoscopic therapy 90. Surgery or retransplantation is typically reserved for patients who fail endoscopic or percutaneous therapy or progress to graft failure 64…”

Section: Non-anastomotic Stricturesmentioning

confidence: 99%

Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment

Fasullo

Patel

Khanna

et al. 2022

BMJ Open Gastroenterol

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Liver transplantation (LT) is the only curative therapy in patients with end-stage liver disease. Long-term survival is excellent, yet LT recipients are at risk of significant complications. Biliary complications are an important source of morbidity after LT, with an estimated incidence of 5%–32%. Post-LT biliary complications include strictures (anastomotic and non-anastomotic), bile leaks, stones, and sphincter of Oddi dysfunction. Prompt recognition and management is critical as these complications are associated with mortality rates up to 20% and retransplantation rates up to 13%. This review aims to summarise our current understanding of risk factors, natural history, diagnostic testing, and treatment options for post-transplant biliary complications.

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Section: Non-anastomotic Stricturesmentioning

confidence: 99%

Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment

Fasullo

Patel

Khanna

et al. 2022

BMJ Open Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Although percutaneous transhepatic biliary drainage (PTBD) insertion is technically easy to perform and has similar efficacy as endoscopic management, 47 maintaining multiple and long-term drains is challenging because of drain malfunctions and patient discomfort. PTBD is, therefore, generally only considered when endoscopic management fails, there is altered surgical anatomy, or the lesions are not amenable to endoscopic therapy (for example, peripheral lesions).…”

Section: Managementmentioning

confidence: 99%

Post-Transplant Biliary Strictures: An Updated Review

et al. 2022

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Liver transplantation (LT) is the only curative therapy in patients with end-stage liver disease with excellent long-term survival; however, LT recipients are at risk of significant complications. Among these complications are biliary complications with an incidence ranging from 5 to 32% and associated with significant post-LT morbidity and mortality. Prompt recognition and management are critical as these complications have been associated with mortality rates up to 19% and retransplantation rates up to 13%. An important limitation of published studies is that a large proportion does not discriminate between anastomotic strictures and nonanastomotic strictures. This review aims to summarize our current understanding of risk factors and natural history, diagnostic testing, and treatment options for post-LT biliary strictures.

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Non-anastomotic Biliary Strictures Following Orthotopic Liver Transplantation: Treatment with Percutaneous Transhepatic Biliary Drainage

Abstract: Percutaneous transhepatic biliary drainage ap-pears to be an effective and safe treatment with high technical success rate and few major complications for non-anastomotic biliary strictures following orthotopic liver transplantation.

Cited by 2 publications

References 0 publications

Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment

Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment

Post-Transplant Biliary Strictures: An Updated Review

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