Abstract. Non-abelian homology of Lie algebras with coefficients in Lie algebras is constructed and studied, generalising the classical Chevalley-Eilenberg homology of Lie algebras. The relationship between cyclic homology and Milnor cyclic homology of non-commutative associative algebras is established in terms of the long exact nonabelian homology sequence of Lie algebras. Some explicit formulae for the second and the third non-abelian homology of Lie algebras are obtained.2000 Mathematics Subject Classification. 17B40, 17B56, 18G10, 18G50. 0. Introduction. The non-abelian homology of groups with coefficients in groups was constructed and investigated in [16,17], using the non-abelian tensor product of groups of Brown and Loday [4, 5] and its non-abelian left derived functors. It generalises the classical Eilenberg-MacLane homology of groups and extends Guin's low dimensional non-abelian homology of groups with coefficients in crossed modules [9], having an interesting application to the algebraic K-theory of non-commutative local rings [9,17].The purpose of this paper is to set up a similar non-abelian homology theory for Lie algebras and is mainly dedicated to state and prove several desirable properties of this homology theory.In [8] Ellis introduced and studied the non-abelian tensor product of Lie algebras which is a Lie structural and purely algebraic analogue of the non-abelian tensor product of groups of Brown and Loday [4,5], arising in applications to homotopy theory of a generalised Van Kampen theorem.Applying this tensor product of Lie algebras, Guin defined the low-dimensional non-abelian homology of Lie algebras with coefficients in crossed modules [10].We construct a non-abelian homology H * (M, N) of a Lie algebra M with coefficients in a Lie algebra N as the non-abelian left derived functors of the tensor product of Lie algebras, generalising the classical Chevalley-Eilenberg homology of Lie algebras and extending Guin's non-abelian homology of Lie algebras [10]. We give an application of our long exact homology sequence to cyclic homology of associative algebras, correcting the result of [10]. In fact, for a unital associative (non-commutative) algebra A we obtain a long exact non-abelian homology available at https://www.cambridge.org/core/terms. https://doi