Nomogram based on high-density lipoprotein cholesterol for the occurrence of preoperative deep vein thrombosis in patients with intertrochanteric femur fracture: a retrospective study

Abstract

Background This study aims to develop a nomogram and forecast the incidence of DVT in individuals suffering from an intertrochanteric femur fracture. Method This work created a nomogram using the R programming language and employed logistic regression to determine independent predicting features. An external validation dataset was used to validate the nomogram. Result The findings demonstrated the independence of LYM (0.02[0.01–0.09], p < 0.001), ALB (0.83[0.74, 0.94], p = 0.002), and HDL-C (0.18[0.04, 0.71], p = 0.014). Good prediction performance with modest errors was shown by the nomogram in both the training and validation groups. Conclusion In conclusion, the nomogram that was created using HDL-C, ALB, and LYM can assist medical professionals in determining the likelihood that DVT will occur.

Development of a nomogram to predict in-hospital mortality of lower extremity deep vein thrombosis patients in intensive care unit

“…One study found higher levels of lactate in fresh venous thrombi rich in red blood cells [25], suggesting that higher lactate levels are associated with higher mortality rates in LEDVT patients, consistent with the results of this study. In three retrospective studies, lymphocytes were found to be a risk factor for DVT [26][27][28] . lymphocytes also play an important role in the body's immune system, and abnormally elevated lymphocytes levels may indicate a potential viral infection, leading to a decrease in platelet count and further aggravating LEDVT, increasing the risk of mortality.…”