Abstract:Recently, measurement technologies allowing to determine the abundance of tens signaling proteins in thousands of single cells became available. The interpretation of this high dimensional end-point time course data is often difficult, because sources of cell-to-cell abundance variation in measured species are hard to determine. Here I present an analytic tool to tackle this problem. By using a recently developed chemical signal generator to manipulate input noise of biochemical networks, measurement of state … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.