List of Tables 3.1 The maximum pitch values for TPFR and ETPFR algorithms compared with half-scan FDK algorithm and full scan FDK algorithm. . 63 3.2 Comparison of amount of filtering operations for 10 images between FDK, TPFR and ETPFR 65 3.3 The mean value and deviation of full-width half maxima (FWHM) for the TPFR and ETFR algorithm compared with FDK algorithm and tangential filtering algorithm 66 3.4 Parameters for resolution phantom (mm) 73 3.5 Parameters for small resolution phantom 73 3.6 Mean values of the standard derivations of regions reconstructed by FDK, Tangential filtering, TPFR and ETPFR, Zou-Pan (HU) .... 74 4.1 The mean value and deviation of full-width half maxima (FWHM) GTASSR, GTFDK, GTTF and GOFTR algorithms Ill 4.2 Mean values of the standard derivations of regions reconstructed by GTFDK, GTASSR, GTTF and GOFTR(HU) 113 NANYANG TECHNOLOGICAL UNIVERSITY SINGAPORE ATTENTION: The Singapore Copyright Act applies to the use of this document. Nanyang Technological University Library XI List of Figures 1.1 Illustration of Step and shot scanning protocol for single slice CT.. . 4 1.2 Illustration of the helical single slice CT 5 1.3 Illustration of multislice CT 1.4 Comparison collimator thickness between MSCT and single slice CT. 2.1 Illustration of the liner integration and parallel geometry for CT.. . 2.2 Illustration of equalangular fan beam geometry for CT 2.3 Illustration of converting parallel projections from fan beam projections. 2.4 Illustration of fan beam sinogram for half scan 2.5 The geometry of the FDK algorithm 3.1 3D geometry of multislice CT scanner 3.2 In plane geometry of multislice CT scanner 3.3 Illustration the definition of slice thickness S 3.4 Geometric descriptions of u, (x c ,y c , z c) T and (x p ,y p , z p) T 3.5 Tilted construction plane 42 NANYANG TECHNOLOGICAL UNIVERSITY SINGAPORE ATTENTION: The Singapore Copyright Act applies to the use of this document. Nanyang Technological University Library LIST OF FIGURES xn 3.6 Plots of d se (P, 7J) with the dotted curve for 7; = 0.4° and solid curve for 7 , = 0° 45 3.7 Illustration of the in plane geometry for s-t coordinate system. Point F is the projection of the point (£ p , rj pj £ p) on £-r\ plane 50 3.8 Geometry of the C position of the ray at iso-center 52 3.9 In plane geometry of the reformation of the cone parallel projection data set 58 3.10 Center and off-center SSPs for FDK algorithm, tangential filtering algorithm, TPFR algorithm and ETPFR algorithm with p = 1.0, M=64 and S=0.625mm 67 3.11 Images for resolution phantom with z = 0, M = 64 and p = 1.0. (300-900HU), reconstructed by FDK algorithm, Tangential filtering algorithm, TPFR algorithm and ETPFR algorithm, respectively. ... 68 3.12 Images for resolution phantom with z = 0, M = 64 and p = 1.2. (300-900HU), reconstructed by FDK algorithm, Tangential filtering algorithm, TPFR algorithm and ETPFR algorithm, respectively. ... 69 3.13 Images for small resolution phantom with z = 0, M = 64 andp = 1.0. (300-900HU), reconstructed by FDK algorithm, Tangential filterin...