An experimental and numerical study to explore the noise reduction mechanism for the inclined leading edge vaned diffuser in centrifugal fans is described. Inclined leading edge vaned diffuser is useful in improving fan performance, increasing operating range, and reducing fan noise. The generation of fan noise is related to the pressure fluctuation on the diffuser vane surface, particularly the leading edge. Numerical results show that pressure fluctuation on the inclined leading edge vaned diffuser surface remarkably decreases, unlike that of the original diffuser. The pressure fluctuation is dominated by the components at the blade passing frequency and its second harmonic.