Abstract:Several biological functions are carried out via complexes that are formed via multimerization of either a single species (homomers) or multiple species (heteromers). Given functional relevance of these complexes, it is arguably desired to maintain their level at a set point and minimize fluctuations around it. Here we consider two simple models of complex formation -one for homomer and another for heteromer of two species -and analyze how important model parameters affect the noise in complex level. In partic… Show more
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