Nodular scleritis and granulomatous polyangiitis (Wegener) mimicking tuberculosis

Abstract

Os autores declaram não haver conflitos de interesse RESUMO ABSTRACTGranulomatous polyangiitis is a systemic disease that may affect any organ, with a predilection for the upper respiratory tract, lungs and kidneys. This article aims to report a case of a patient with atypical nodular scleritis as the initial manifestation of granulomatous polyangiitis (Wegener), mimicking a case of tuberculosis. The patient presented ocular hyperemia and lower progressive visual acuity for 1.5 years, followed by eye pain for two months. The patient had subpleural nodules with soft tissue density, increased pulmonary lymph nodes and discrete bilateral pleural thickening, with negative alcohol-resistant acid bacilli (BAAR). The histological diagnosis revealed a granulomatous vasculitis suggestive of non-infectious vasculitis (granulomatous polyangiitis). Cyclophosphamide pulse therapy was initiated.

Heart conduction system defects and sustained ventricular tachycardia complications in a patient with granulomatosis with polyangiitis. A case report and literature review

“…( 1 , 5 ) In approximately 8% to 16% of the cases, the eyes can be the only site of affliction at the initial presentation, while persistent symptoms are recorded in 87% of all of patients. ( 4 ) A positive c-ANCA or tissue biopsy are important for the initial diagnosis ( 1 ) in order to exclude other diseases with a similar presentation.…”