Nodular Non-Diabetic Cutaneous Xanthomatosis with Hypercholesterolæmia and Atypical Histological Features

Clinical and pathologic findings of paraneoplastic dermatoses

“…Multicentric reticulohistiocytosis was first described by Weber and Freudenthal in 1937, 76 and its association with malignancy was first proposed by Barrow and Holubar in 1969. 77,78,79 Demographics.…”

Giant‐cell tumours of soft tissues

“…Within this group of xanthomatous lesions, the rare condition usually known as generalised reticulohistiocytosis is to be distinguished from giant-cell tumour of soft tissues by the presence of multiple lesions, as well as by differences of histological structure. It is a systemic condition that may involve joints, lymphnodes, larynx, endocardium, bone marrow and muscles in addition to skin and subcutaneous tissue (Montgomery and O'Leary, 1934;Weber and Freudenthal, 1937;Weber, 1943;Warin et al, 1957;Lye11 and Carr, 1959).…”

Multicentric reticulohistiocytosis

“…Weber and Freudenthal, 1 in 1937, published the first description of multicentric reticulohistiocytosis (MR) and, in 1949, Portugal et al. , 2 in Brazil, proved the histiocytic nature of MR. Goltz and Laymon 3 were the first to introduce the term MR.…”