2007
DOI: 10.1148/rg.272065061
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Nodular Ground-Glass Opacity at Thin-Section CT: Histologic Correlation and Evaluation of Change at Follow-up

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Cited by 249 publications
(179 citation statements)
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“…However, several methodologic problems hinder diagnosis of GGO predominant-type lesions by transbronchial biopsy (TBB): (1) the lesions may not be visible under X-ray fluoroscopic 6 guidance; (2) there is difficulty in identifying accessible bronchial routes to reach peripheral lesions within the time limitation of the procedure; and (3) it is difficult to confirm whether biopsy forceps or a brush can accurately reach the lesions. We previously reported that EBUS-GS could be useful in clinical practice for diagnosing GGO predominant-type lesions in the peripheral lung [14,15], and recent studies have reported that some of these lesions are likely to be diagnosed as adenocarcinoma or precancerous lesions [14,[16][17][18][19].…”
Section: Introductionmentioning
confidence: 99%
“…However, several methodologic problems hinder diagnosis of GGO predominant-type lesions by transbronchial biopsy (TBB): (1) the lesions may not be visible under X-ray fluoroscopic 6 guidance; (2) there is difficulty in identifying accessible bronchial routes to reach peripheral lesions within the time limitation of the procedure; and (3) it is difficult to confirm whether biopsy forceps or a brush can accurately reach the lesions. We previously reported that EBUS-GS could be useful in clinical practice for diagnosing GGO predominant-type lesions in the peripheral lung [14,15], and recent studies have reported that some of these lesions are likely to be diagnosed as adenocarcinoma or precancerous lesions [14,[16][17][18][19].…”
Section: Introductionmentioning
confidence: 99%
“…However, not all SSNs are malignant. In fact, SSNs include various histologic backgrounds including many benign conditions, such as focal interstitial fibrosis, eosinophilic pneumonia, thoracic endometriosis, and focal hemorrhage (5,6). Nevertheless, in consideration of the significance of lung cancer, we focus on SSNs in relation to adenocarcinomas in this review.…”
mentioning
confidence: 99%
“…The formation mechanism of different ILD group-glass opacities is not exactly the same and can be caused by the incomplete inflation of pulmonary alveoli caused by inflammation, edema, fibrosis, or tumors (Clement et al, 2010). Ground-glass opacities of acute interstitial pneumonia (AIP) reflect the formation of transparent lung membrane (Park et al, 2007). Siegel et al (2001) reported that lesions were distributed around bronchi and presented lobular (punctate) or patchy density-increased shadows, which was similar to tuberculous pneumonia.…”
Section: Lobular Ground-glass Opacitiesmentioning
confidence: 99%