Nodular colloid milium mimicking keloid

Abstract

Colloid milium is a rare cutaneous deposit disease that usually presents clinically by the development of yellowish translucent or flesh-colored papules or plaques on sun-exposed skin. Histologically, it is characterized by the presence of colloid in the dermal papillae. In this case report, we present a 52-year-old man who presented with a nodule on his upper lip that mistakenly was diagnosed and treated as keloid.

Colloid milium, an expression of excessive sun exposure in Ecuadorian patients

“…Pigmented CM has been related to hydroquinone use, as our second case, and presents lesions resembling caviar‐like papules darker than the patient's normal skin along with atrophy . Finally, the nodular type or nodular colloid degeneration has solitary or multiples plaques or nodules of up to 5 cm with a slightly lumpy surface …”

“…Differential diagnosis includes sarcoidosis, Favre‐Racouchot disease, trichoepitheliomas, sebaceous hyperplasias, lipoid proteinosis, retention cysts, molluscum contagiosum, papular mucinosis, syringomas, calcinosis cutis, milia, and amyloidosis …”

“…There is currently no single effective treatment, but the use of topical retioids, systemic ascorbic acid, dermabrasion, chemical peels, cryotherapy and topical photodynamic therapy, ablative or nonablative Er: YAG and CO 2 laser has been reported, the latter being an alternative that produces a good therapeutic outcome lasting many months with few sessions …”