2021
DOI: 10.1007/s12011-021-02658-6
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Nocturnal Salivary Fluoride Bioavailability After Brushing with a High-fluoride Dentifrice

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Cited by 2 publications
(4 citation statements)
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“…This availability of the remaining intraoral F is important in caries control, as F retained in oral reservoirs plays a key role in de‐remineralization processes 8 . Furthermore, because they can increase this availability for most of the day, they can be considered a useful therapy for patients at a high risk of caries, 23 such as orthodontic patients, due to the increase in retention sites of biofilm 5 and in the elderly, who have impaired motor capacity with age 9 and reduced salivary flow levels 21 …”
Section: Discussionmentioning
confidence: 99%
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“…This availability of the remaining intraoral F is important in caries control, as F retained in oral reservoirs plays a key role in de‐remineralization processes 8 . Furthermore, because they can increase this availability for most of the day, they can be considered a useful therapy for patients at a high risk of caries, 23 such as orthodontic patients, due to the increase in retention sites of biofilm 5 and in the elderly, who have impaired motor capacity with age 9 and reduced salivary flow levels 21 …”
Section: Discussionmentioning
confidence: 99%
“…Fifteen adults, aged between 20 and 32 years, participated in this study; there were eight men and seven women, with good general and oral health, who lived in a municipality with fluoridated public water supply (0.6-0.8 ppm F). The sample size was determined based on previous findings 21,22 using a similar experimental protocol, with an effect size of 0.25 (for saliva F concentration as the primary outcome), with a sample power of 0.80 and a total of ten measurements. During three experimental phases, participants were randomly assigned to one of three groups (depending on the dentifrice they were using): two high-fluoride dentifrices (5000 ppm F) and one of conventional concentration (1450 ppm) used on different days.…”
Section: Experimental Designmentioning
confidence: 99%
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“…The fluoride level in the oral fluids, including saliva, is considered a proxy variable for caries controlling effect of fluoride applications, including fluoride toothpaste [11]. Most published studies on high-dosage fluoride toothpaste have reported the salivary fluoride concentration after a single or very few toothbrushing sessions and/or only during the first few hours after exposure(s) [12][13][14][15][16][17][18][19][20]. These studies show that a single or few exposures to high-fluoride toothpaste result in higher salivary fluoride levels during the first few hours after exposure than seen after the use of toothpaste with up to 1500 ppm fluoride.…”
Section: Introductionmentioning
confidence: 99%