Nocturnal hypoglycemia detected with the continuous glucose monitoring system in pediatric patients with type 1 diabetes

Glycemic Characteristics in Continuously Monitored Patients With Type 1 and Type 2 Diabetes

“…In fact, type 1 diabetic subjects spent Ͼ2 h/day in a state of frank hypoglycemia. This disturbing frequency of nocturnal hypoglycemia often goes undetected by standard self-monitoring of blood glucose and has been recognized previously by other investigators using continuous glucose monitoring in both type 1 and type 2 diabetic patients (10,18,22,23,(33)(34)(35). Hypoglycemia, often with unconsciousness, appears to be increased in children and adolescents with type 1 diabetes subjected to intensive insulin therapy (36).…”

Clinical Use of Continuous Glucose Monitoring in Pediatrics

“…Most of these episodes occurred between 9 PM and 1 AM. 20 In 2003 Amin et al evaluated 28 prepubertal children (<12 years old) on injection regimens who wore sensors for 3 consecutive days and nights and found hypoglycemic prevalence of 10.1% (mean 2.6 h/subject/day) particularly between 4 and 7:30 AM. Risk factors included younger age, greater daily insulin dose, and increased weight.…”

“…A recent analysis by Forlenza revealed differences in the average AGP glycemic patterns for the JDRF-CGM dataset when stratified by age group (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24), and ‡25 years) and HbA1c. They report that for a given HbA1c level, all age groups were significantly different, with older patients having lower averages and less variability than younger patients.…”

Diabetes Management in Correctional Institutions

“…Because children and adolescents are reported to have higher rates of nocturnal hypoglycemia (13), consideration should be given regarding the use of episodic overnight blood glucose monitoring in these patients. In particular, this should be considered in children and adolescents who have recently had their overnight insulin dose changed.…”