Nociception related biomolecules in the adult human saliva: A scoping review with additional quantitative focus on cortisol
Roxaneh Zarnegar,
Angeliki Vounta,
Qiuyuan Li
et al.
Abstract:Nociception related salivary biomolecules can be useful patients who are not able to self-report pain. We present the existing evidence on this topic using the PRISMA-ScR guidelines and a more focused analysis of cortisol change after cold pain induction using the direction of effect analysis combined with risk of bias analysis using ROBINS-I. Five data bases were searched systematically for articles on adults with acute pain secondary to disease, injury or experimentally induced pain. 43 articles met the incl… Show more
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