Nocardiosis Causing Pedal Actinomycetoma: A Case Report and Review of the Literature

Gosselink, Carrie P.; Thomas, James L.; Brahmbhatt, Sachin; Patel, Nilam K.; Vindas, Jose

doi:10.1053/j.jfas.2008.04.009

Cited by 6 publications

(5 citation statements)

References 10 publications

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“…In rare instances N. asteroides , commonly the cause of pulmonary nocardiosis and Actinomyces israelli , commonly the cause of Actinomyces produce a mycetoma on the feet or hands. [389] Eumycetoma is caused by a group of fungi with thick, septate hyphae, including Allescheria boydii , Madurella griesia and Madurella mycetomi. [9]…”

Section: Discussionmentioning

confidence: 99%

Histological diagnosis of madura foot (mycetoma): A must for definitive treatment

Alam

Maheshwari

Bhargava

et al. 2009

J Global Infect Dis

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Section: Discussionmentioning

confidence: 99%

Histological diagnosis of madura foot (mycetoma): A must for definitive treatment

Alam

Maheshwari

Bhargava

et al. 2009

J Global Infect Dis

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“…Occasional reports of mycetoma appears in temperate regions of European countries such as Germany, Albania, Bulgaria, Greece, Italy, and Turkey [ 11 , 39 – 46 ]. In France, mycetoma has been reported in migrants from Africa [ 7 , 8 ]. Sporadic cases have also been reported from subtropical regions of south-western United States [ 47 ].…”

Section: Distribution Of Mycetomamentioning

confidence: 99%

“…These ruptured nodules continue as a sinus tract discharging fluid which contains grains, and is usually characterised by alternating episodes of healing and breakdown as the affected area progressively enlarges, becomes more oedematous, nodulated and deformed [ 47 ]. Pain is hardly felt at this stage and has only been reported in 15% of patients [ 8 ]. This absence of pain has been attributed to production of anaesthetic substances and only in rare cases, pain can results from super-imposed bacterial infection, bone expansion or nerve damage in the later part of the disease course [ 8 ].…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Pain is hardly felt at this stage and has only been reported in 15% of patients [ 8 ]. This absence of pain has been attributed to production of anaesthetic substances and only in rare cases, pain can results from super-imposed bacterial infection, bone expansion or nerve damage in the later part of the disease course [ 8 ].…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Though uncertainty hovers on its actual global incidence, a field survey from West Nile State of Sudan, a country uniquely believed to be the most endemic in the world, yielded a prevalence of 14.5/1000 population in 2010 [ 1 , 5 ]. Several autochthonous and imported cases have also been reported from Europe [ 6 – 8 ]. Prolonged diagnostic delays complicate mycetoma as seen in a patient (infected with Aspergillus nidulans ) from Senegal with a diagnostic delay of 15 years [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Mycetoma: a clinical dilemma in resource limited settings

Pembi

Dumre

John

et al. 2018

Ann Clin Microbiol Antimicrob

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BackgroundMycetoma is a chronic mutilating disease of the skin and the underlying tissues caused by fungi or bacteria. Although recently included in the list of neglected tropical diseases by the World Health Organization, strategic control and preventive measures are yet to be outlined. Thus, it continues to pose huge public health threat in many tropical and sub-tropical countries. If not detected and managed early, it results into gruesome deformity of the limbs. Its low report and lack of familiarity may predispose patients to misdiagnosis and delayed treatment initiation. More so in situation where diagnostic tools are limited or unavailable, little or no option is left but to clinically diagnose these patients. Therefore, an overview of clinical course of mycetoma, a suggested diagnostic algorithm and proposed use of materials that cover the exposed susceptible parts of the body during labour may assist in the prevention and improvement of its management. Furthermore, early reporting which should be encouraged through formal and informal education and sensitization is strongly suggested.Main textAn overview of the clinical presentation of mycetoma in the early and late phases, clues to distinguish eumycetoma from actinomycetoma in the field and the laboratory, differential diagnosis and a suggested diagnostic algorithm that may be useful in making diagnosis amidst the differential diagnosis of mycetoma is given. Additionally, a proposed preventive measures which may be helpful in the community is also provided. Since treatment is currently based on expert opinion, we encourage active research to establish treatment guideline for it.ConclusionSince delay in visiting health facility results into gruesome complication, early presentation, recognition and initiation of appropriate choice of regimen is helpful in reducing complications. The clinical overview of mycetoma and the suggested algorithm may enhance suspicion and possibly increase recognition of mycetoma in the community and further guide in differentiation of eumycetoma from actinomycetoma. There is an urgent need for research funding for mycetoma, a disease plagued by severe physical disabilities and social stigma leading to isolation.Electronic supplementary materialThe online version of this article (10.1186/s12941-018-0287-4) contains supplementary material, which is available to authorized users.

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Bacterial Infections

2011

Andrews' Diseases of the Skin

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Nocardiosis Causing Pedal Actinomycetoma: A Case Report and Review of the Literature

Cited by 6 publications

References 10 publications

Histological diagnosis of madura foot (mycetoma): A must for definitive treatment

Histological diagnosis of madura foot (mycetoma): A must for definitive treatment

Mycetoma: a clinical dilemma in resource limited settings

Bacterial Infections

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