Nocardial pneumonia as an opportunistic infection in Covid treated patient

Siddiqui, Hoda; Areena,; Agarwal,; Manoj,; Dixit,; nitin,

doi:10.1016/j.ijtb.2021.08.022

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Nocardia is a Gram-positive that is ubiquitous in nature, primarily found in soil and humid environments. It frequently causes infections in immunocompromised patients, including those undergoing solid organ transplantation, suffering from chronic lung disease, diabetes, malignancy, or using long-term steroid therapy (3)(4)(5)(6). Pulmonary nocardiosis is the most common type, presenting with nonspecific symptoms such as fever, cough, and chest pain, as well as CT imaging findings of lung consolidation, nodules/masses, ground-glass opacity, and centrilobular nodules.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report

Cao,

Sun,

Chen

2023

Front. Med.

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BackgroundNocardiosis is an opportunistic infection that primarily affects immunocompromised patients. Pulmonary nocardiosis is the most prevalent form, but can also spread to other organs. Potential causes contributing to opportunistic infection may include immunosuppression and disruption of tight junctions, both of which can result from COVID-19.Case presentationWe reported a case of a 68-year-old male patient who presented with a 10-day history of fever, cough, and productive sputum. Upon physical examination, velcro rales were detected in the right lung, while breath sounds in the left lung were clear. The patient had previously undergone left lung transplantation due to idiopathic pulmonary fibrosis four years ago. He was initially hospitalized and treated for COVID-19 but was readmitted due to worsening symptoms. Subsequently, pulmonary nocardiosis was diagnosed utilizing metagenomic next-generation sequencing of bronchoalveolar lavage fluid. The above-mentioned condition was improved following treatment with cancidas and linezolid. Now, he is under regular follow-up.ConclusionThis case highlights the complexity of COVID-19 and the occurrence of secondary opportunistic infections, which require further investigation.

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Section: Discussionmentioning

confidence: 99%

Pulmonary nocardiosis following COVID-19 in a patient with idiopathic pulmonary fibrosis and lung transplantation: a case report

Cao,

Sun,

Chen

2023

Front. Med.

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“…To the best of our knowledge, there are only three case reports to date. [ 1 , 2 ] Nocardia species are ubiquitous saprophytic gram-positive bacteria of the “aerobic actinomycetes” group.Click or tap here to enter text. [ 3 ] The primary route of transmission is inhalational, from environmental sources.…”

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confidence: 99%