“…The in vitro sensitivities can be misleading in treatment. Unlike Actinomyces, Nocardia is almost invariably resistant to penicillin, while streptomycin, erythromycin, novobiocin, and chloramphenicol have been reported to be effective in some patients (Hathaway and Mason, 1962;Larsen, Diamond, and Collins, 1959). Seabury and Dascomb (1964) were unable to show any definite effect with amphotericin B and advocate sulphadiazine and cycloserine in the initial treatment of nocardiosis.…”