Noble Metal Composite Porous Silk Fibroin Aerogel Fibers

Mitropoulos, Alexander N.; Burpo, F. John; Nguyen, C.; Nagelli, Enoch A.; Ryu, Madeline Y.; Wang, Jenny L; Sims, R. Kenneth; Woronowicz, Kamil; Wickiser, J. Kenneth

doi:10.3390/ma12060894

Cited by 37 publications

(30 citation statements)

References 44 publications

(62 reference statements)

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“…These materials were fabricated by standard methods (dissolution in HFIP, solution casting, solvent evaporation, and optional ethanol treatment). HFIP, a highly efficient organic solvent for fibroin solubilization, has been used for fabrication of advanced protein-based materials [27]. FbMA-F-aq and FbMA-F-et films were fabricated via TPO-initiated photochemical polymerization of the novel methacrylated Fb derivative FbMA.…”

Section: Film Fabricationmentioning

confidence: 99%

The Mechanical Properties, Secondary Structure, and Osteogenic Activity of Photopolymerized Fibroin

et al. 2020

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Previously, we have described the preparation of a novel fibroin methacrylamide (FbMA), a polymer network with improved functionality, capable of photocrosslinking into Fb hydrogels with elevated stiffness. However, it was unclear how this new functionality affects the structure of the material and its beta-sheet-associated crystallinity. Here, we show that the proposed method of Fb methacrylation does not disturb the protein’s ability to self-aggregate into the stable beta-sheet-based crystalline domains. Fourier transform infrared spectroscopy (FTIR) shows that, although the precursor ethanol-untreated Fb films exhibited a slightly higher degree of beta-sheet content than the FbMA films (46.9% for Fb-F-aq and 41.5% for FbMA-F-aq), both materials could equally achieve the highest possible beta-sheet content after ethanol treatment (49.8% for Fb-F-et and 49.0% for FbMA-F-et). The elasticity modulus for the FbMA-F-et films was twofold higher than that of the Fb-F-et as measured by the uniaxial tension (130 ± 1 MPa vs. 64 ± 6 MPa), and 1.4 times higher (51 ± 11 MPa vs. 36 ± 4 MPa) as measured by atomic force microscopy. The culturing of human MG63 osteoblast-like cells on Fb-F-et, FbMA-F-et-w/oUV, and FbMA-F-et substrates revealed that the photocrosslinking-induced increment of stiffness increases the area covered by the cells, rearrangement of actin cytoskeleton, and vinculin distribution in focal contacts, altogether enhancing the osteoinductive activity of the substrate.

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Section: Film Fabricationmentioning

confidence: 99%

The Mechanical Properties, Secondary Structure, and Osteogenic Activity of Photopolymerized Fibroin

et al. 2020

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“…There are very few reports of silk fibroin materials with the presence of magnetic particles: magnetic silk fibroin composite nanofibers, magnetic silk fibroin e-gel scaffolds, silk fibroin films decorated with magnetic particles, and silk fibroin/chitosan/magnetite scaffolds have been studied [ 196 , 197 , 198 , 199 ]. Silk fibroin-based materials with addition of noble metals (tetrachloropalladate (II) (Na 2 PdCl 4 ), potassium tetrachloroplatinate (II) (K 2 PtCl 4 ), gold chloride trihydrate (HAuCl 4 ·3H 2 O), silver nitrate (AgNO 3 ), tetrachloroauric acid (HAuCl 4 )) also can be found in the literature [ 200 , 201 ]. They can be used for biological sensing, energy storage applications, and in biotechnology such as immunoassay, biosensor, DNA identification and inspection, gene therapy, and will emerge in further research [ 200 , 201 ].…”

Section: Blendingmentioning

confidence: 99%

“…Silk fibroin-based materials with addition of noble metals (tetrachloropalladate (II) (Na 2 PdCl 4 ), potassium tetrachloroplatinate (II) (K 2 PtCl 4 ), gold chloride trihydrate (HAuCl 4 ·3H 2 O), silver nitrate (AgNO 3 ), tetrachloroauric acid (HAuCl 4 )) also can be found in the literature [ 200 , 201 ]. They can be used for biological sensing, energy storage applications, and in biotechnology such as immunoassay, biosensor, DNA identification and inspection, gene therapy, and will emerge in further research [ 200 , 201 ].…”

Section: Blendingmentioning

confidence: 99%

How to Improve Physico-Chemical Properties of Silk Fibroin Materials for Biomedical Applications?—Blending and Cross-Linking of Silk Fibroin—A Review

Grabska-Zielińska

Sionkowska

2021

Materials

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This review supplies a report on fresh advances in the field of silk fibroin (SF) biopolymer and its blends with biopolymers as new biomaterials. The review also includes a subsection about silk fibroin mixtures with synthetic polymers. Silk fibroin is commonly used to receive biomaterials. However, the materials based on pure polymer present low mechanical parameters, and high enzymatic degradation rate. These properties can be problematic for tissue engineering applications. An increased interest in two- and three-component mixtures and chemically cross-linked materials has been observed due to their improved physico-chemical properties. These materials can be attractive and desirable for both academic, and, industrial attention because they expose improvements in properties required in the biomedical field. The structure, forms, methods of preparation, and some physico-chemical properties of silk fibroin are discussed in this review. Detailed examples are also given from scientific reports and practical experiments. The most common biopolymers: collagen (Coll), chitosan (CTS), alginate (AL), and hyaluronic acid (HA) are discussed as components of silk fibroin-based mixtures. Examples of binary and ternary mixtures, composites with the addition of magnetic particles, hydroxyapatite or titanium dioxide are also included and given. Additionally, the advantages and disadvantages of chemical, physical, and enzymatic cross-linking were demonstrated.

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“…Aerogel fibers not only enrich the morphology of aerogels but also expand the applicability of aerogels in different fields and contexts. In addition to thermal insulation applications [ 25 , 26 ], aerogel fibers could also be used in other fields, such as adsorption [ 27 , 28 , 29 ], biological sensing [ 30 ], and supercapacitors [ 31 ]. As a result of these potential advantages, it is essential to develop different strategies to obtain high-strength aerogel fibers.…”

Section: Introductionmentioning

confidence: 99%

Robust Silica-Bacterial Cellulose Composite Aerogel Fibers for Thermal Insulation Textile

Sai

Wang

Miao

et al. 2021

Gels

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Aerogels are nanoporous materials with excellent properties, especially super thermal insulation. However, owing to their serious high brittleness, the macroscopic forms of aerogels are not sufficiently rich for the application in some fields, such as thermal insulation clothing fabric. Recently, freeze spinning and wet spinning have been attempted for the synthesis of aerogel fibers. In this study, robust fibrous silica-bacterial cellulose (BC) composite aerogels with high performance were synthesized in a novel way. Silica sol was diffused into a fiber-like matrix, which was obtained by cutting the BC hydrogel and followed by secondary shaping to form a composite wet gel fiber with a nanoscale interpenetrating network structure. The tensile strength of the resulting aerogel fibers reached up to 5.4 MPa because the quantity of BC nanofibers in the unit volume of the matrix was improved significantly by the secondary shaping process. In addition, the composite aerogel fibers had a high specific area (up to 606.9 m2/g), low density (less than 0.164 g/cm3), and outstanding hydrophobicity. Most notably, they exhibited excellent thermal insulation performance in high-temperature (210 °C) or low-temperature (−72 °C) environments. Moreover, the thermal stability of CAFs (decomposition temperature was about 330 °C) was higher than that of natural polymer fiber. A novel method was proposed herein to prepare aerogel fibers with excellent performance to meet the requirements of wearable applications.

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Noble Metal Composite Porous Silk Fibroin Aerogel Fibers

Cited by 37 publications

References 44 publications

The Mechanical Properties, Secondary Structure, and Osteogenic Activity of Photopolymerized Fibroin

The Mechanical Properties, Secondary Structure, and Osteogenic Activity of Photopolymerized Fibroin

How to Improve Physico-Chemical Properties of Silk Fibroin Materials for Biomedical Applications?—Blending and Cross-Linking of Silk Fibroin—A Review

Robust Silica-Bacterial Cellulose Composite Aerogel Fibers for Thermal Insulation Textile

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