Noble metal-based nanomaterials as antibacterial agents

Ye, Lei; Cao, Zhongming; Liu, Xiangmei; Cui, Zhenduo; Li, Zhaoyang; Liang, Yanqin; Zhu, Shengli; Wu, Shuilin

doi:10.1016/j.jallcom.2022.164091

Cited by 75 publications

(38 citation statements)

References 186 publications

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“…Many innovative materials are still at the designing stage [ 5 ]. For this reason, the usage of well-known materials, based on metals is back in the spotlight [ 6 , 7 , 8 ]. Metals, such as silver or copper, can be toxic to bacteria because of their antimicrobial activities even at exceptionally low concentrations.…”

Section: Introductionmentioning

confidence: 99%

Functionalised Anodised Aluminium Oxide as a Biocidal Agent

Schabikowski

Laskowska

Kowalczyk

et al. 2022

IJMS

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In this article, we describe the antimicrobial properties of a new composite based on anodic aluminium oxide (AAO) membranes containing propyl-copper-phosphonate units arranged at a predetermined density inside the AAO channels. The samples were prepared with four concentrations of copper ions and tested as antimicrobial drug on four different strains of Escherichia coli (K12, R2, R3 and R4). For comparison, the same strains were tested with three types of antibiotics using the minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests. Moreover, DNA was isolated from the analysed bacteria which was additionally digested with formamidopyrimidine-DNA glycosylase (Fpg) protein from the group of repair glycosases. These enzymes are markers of modified oxidised bases in nucleic acids produced during oxidative stress in cells. Preliminary cellular studies, MIC and MBC tests and digestion with Fpg protein after modification of bacterial DNA suggest that these compounds may have greater potential as antibacterial agents than antibiotics such as ciprofloxacin, bleomycin and cloxacillin. The described composites are highly specific for the analysed model Escherichia coli strains and may be used in the future as new substitutes for commonly used antibiotics in clinical and nosocomial infections in the progressing pandemic era. The results show much stronger antibacterial properties of the functionalised membranes on the action of bacterial membranes in comparison to the antibiotics in the Fpg digestion experiment. This is most likely due to the strong induction of oxidative stress in the cell through the breakdown of the analysed bacterial DNA. We have also observed that the intermolecular distances between the functional units play an important role for the antimicrobial properties of the used material. Hence, we utilised the idea of the 2D solvent to tailor them.

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Section: Introductionmentioning

confidence: 99%

Functionalised Anodised Aluminium Oxide as a Biocidal Agent

Schabikowski

Laskowska

Kowalczyk

et al. 2022

IJMS

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“…Meanwhile, NIR laser focusing on the target area possesses the advantages of promoting blood circulation and relieving tissue inflammation. [182] At present, a variety of photothermal conversion agents including precious metal nanoparticles, [31,69] carbonbased nanostructures, [183] and semiconductor nanomaterials [178] have been explored and applied in the field of photothermal antibacterial. Thanks to the 1.8 eV bandgap of the 2D MoS 2 , the photothermal conversion efficiency of the single-layer MoS 2based material is far ahead of other 2D TMDCs.…”

Section: Photothermal Antibacterialmentioning

confidence: 99%

2D Molybdenum Sulfide‐Based Materials for Photo‐Excited Antibacterial Application

Chen

Luo

Liu

et al. 2022

Adv Healthcare Materials

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Bacterial infections have seriously threatened human health and the abuse of natural or artificial antibiotics leads to bacterial resistance, so development of a new generation of antibacterial agents and treatment methods is urgent. 2D molybdenum sulfide (MoS 2 ) has good biocompatibility, high specific surface area to facilitate surface modification and drug loading, adjustable energy bandgap, and high near-infrared photothermal conversion efficiency (PCE), so it is often used for antibacterial application through its photothermal or photodynamic effects. This review comprehensively summarizes and discusses the fabrication processes, structural characteristics, antibacterial performance, and the corresponding mechanisms of MoS 2 -based materials as well as their representative antibacterial applications. In addition, the outlooks on the remaining challenges that should be addressed in the field of MoS 2 are also proposed.

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“…4–8 Non-drug antibacterial nanomaterials have attracted increasing attention because of their promising antibacterial and antimicrobial capacities, for example, Ag, Au, and TiO 2 nanoparticles (NPs). 9–11 Some non-drug nanomaterials have exhibited effective long-lasting antibacterial performance and potential value in clinical treatments, for example, Cu/Ti–6Al–4V, Cu/GO, and polylactic acid (PLLA)/Ag. 8,12,13 In 2020, Liu et al successfully synthesized the “inside–outside” Ag-NPs-loaded composite fibers, and Ag-NPs were uniformly distributed on the inner surface of the PLLA fibers.…”

Section: Introductionmentioning

confidence: 99%