Abstract:Mesangial IgA glomerulonephritis is now well documented as the commonest form of idiopathic glomerulonephritis and is a major cause of endstage renal failure in most countries. It has a high risk for progression (20%) and effective treatment is not available. The etiology of IgA nephropathy is unknown. As in other progressive glomerulonephritis converge on a common avenue of sclerosis, by which specialized cellular structures are replaced by collagen and mesenchymal matrix. Currently there is much attention be… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.